Glycogen Phosphorylase Inhibitor
Synonym(s):1-(3-(3-(2-Chloro-4,5-difluorobenzoyl)ureido)-4-methoxyphenyl)-3-methylurea;Glycogen Phosphorylase Inhibitor - CAS 648926-15-2 - Calbiochem
- CAS NO.：648926-15-2
- Empirical Formula: C17H15ClF2N4O4
- Molecular Weight: 412.78
- MDL number: MFCD22050364
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-13 13:05:00
What is Glycogen Phosphorylase Inhibitor?
Description
Glycogen phosphorylase in the liver, muscle, and brain initiate glycogenolysis by releasing glucose-1-phosphate from glycogen. Glycogen phosphorylase inhibitor is a cell-permeable acyl urea first identified as an inhibitor of human liver glycogen phosphorylase (IC50 = 53 nM). It blocks glucagon-induced hepatic glycogenolysis in vivo. Glycogen phosphorylase inhibitor has been used to study glycogen utilization in human liver HepG2 cells, retinal explants, and human T lymphocyte Kit 225 cells.
The Uses of Glycogen Phosphorylase Inhibitor
Glycogen Phosphorylase Inhibitor is used in biological studies to evaluate glycogen utilization in human liver HepG2 cells.
What are the applications of Application
Glycogen Phosphorylase Inhibitor is a cell permeable urea compound and potent inhibitor of glycogen phosphorylase
Properties of Glycogen Phosphorylase Inhibitor
| Density | 1.490±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF:5.0(Max Conc. mg/mL);12.11(Max Conc. mM) DMSO:5.0(Max Conc. mg/mL);12.11(Max Conc. mM) |
| form | White powder solid. |
| pka | 8.47±0.46(Predicted) |
Safety information for Glycogen Phosphorylase Inhibitor
Computed Descriptors for Glycogen Phosphorylase Inhibitor
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