gitaloxin
- CAS NO.:3261-53-8
- Empirical Formula: C42H64O15
- Molecular Weight: 808.95
- MDL number: MFCD00046279
- EINECS: 221-864-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2022-12-21 16:56:50
What is gitaloxin?
Originator
Gitaloxin,Shanghai Lansheng Corporation
Definition
ChEBI: A cardenolide glycoside that is gitoxin in which the 16beta-hydroxy group has been formylated.
Manufacturing Process
0.2 g gitoxin was dissolved in 15 ml of dimethylformamide and mixed with 2 ml of acetanhydride, 3 ml formic acid (98%) and 2 ml triethylamine or pyridine. The reaction mixture stood for 60 min. at room temperature, then it was diluted with water, a precipitated product was filtered off. A filtrate was shook with chloroform 2 times. Chloroform was distilled to dryness and the residue was added to the precipitate. 16-Formylgitoxin was isolated by fraction crystallization. MP: 250°-253°C, yield about 50%.
Therapeutic Function
Cardiotonic
Properties of gitaloxin
| Melting point: | 251.5°C |
| Boiling point: | 674.74°C (rough estimate) |
| Density | 1.1231 (rough estimate) |
| refractive index | 1.5940 (estimate) |
Safety information for gitaloxin
Computed Descriptors for gitaloxin
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