gitaloxin

CAS NO.：3261-53-8
Empirical Formula: C42H64O15
Molecular Weight: 808.95
MDL number: MFCD00046279
EINECS: 221-864-7
SAFETY DATA SHEET (SDS)
Update Date: 2022-12-21 16:56:50

What is gitaloxin?

Originator

Gitaloxin,Shanghai Lansheng Corporation

Definition

ChEBI: A cardenolide glycoside that is gitoxin in which the 16beta-hydroxy group has been formylated.

Manufacturing Process

0.2 g gitoxin was dissolved in 15 ml of dimethylformamide and mixed with 2 ml of acetanhydride, 3 ml formic acid (98%) and 2 ml triethylamine or pyridine. The reaction mixture stood for 60 min. at room temperature, then it was diluted with water, a precipitated product was filtered off. A filtrate was shook with chloroform 2 times. Chloroform was distilled to dryness and the residue was added to the precipitate. 16-Formylgitoxin was isolated by fraction crystallization. MP: 250°-253°C, yield about 50%.

Therapeutic Function

Cardiotonic

Properties of gitaloxin

Melting point:	251.5°C
Boiling point:	674.74°C (rough estimate)
Density	1.1231 (rough estimate)
refractive index	1.5940 (estimate)

Safety information for gitaloxin

Computed Descriptors for gitaloxin

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