Ginsenoside Rh2
Synonym(s):(3β,12β)-12,20-Dihydroxydammar-24-en-3-yl-β-D -glucopyranoside;20(S)-Ginsenoside-Rh2
- CAS NO.：78214-33-2
- Empirical Formula: C36H62O8
- Molecular Weight: 622.88
- MDL number: MFCD00800712
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 10:31:43
What is Ginsenoside Rh2?
Description
Ginsenoside Rh2 is a steroid glycoside found in plants of the genus Panax that has diverse biological activities. It inhibits release of β-hexosaminidase from RBL-2H3 cells (IC50 = 100 μM) and inhibits the IgE-dependent passive cutaneous anaphylaxis reaction in mice at a dose of 25 mg/kg. It inhibits growth of HRA ovarian and BxPC-3 pancreatic cancer cells in a dose-dependent manner. In vivo, ginsenoside Rh2 decreases immobility time in the forced swim test in a mouse model of colorectal carcinoma. Ginsenoside Rh2 also reduces infarct volume in a rat model of ischemia-reperfusion-induced brain injury.
Chemical properties
White solid
The Uses of Ginsenoside Rh2
20(S)-Ginsenoside Rh2 is a bioactive metabolite of the ginsenoside component of Panax ginseng that has been shown to exhibit antibacterial effects in vitro.
What are the applications of Application
20(S)- Ginsenoside Rh2 is a plant glycoside with anti-cancer proliferation and chemopreventive effects
Definition
ChEBI: A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.
Properties of Ginsenoside Rh2
| Melting point: | 139-144 °C |
| Boiling point: | 726.4±60.0 °C(Predicted) |
| Density | 1.19±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml |
| form | neat |
| pka | 12.91±0.70(Predicted) |
| form | Solid |
| color | White |
| CAS DataBase Reference | 78214-33-2(CAS DataBase Reference) |
Safety information for Ginsenoside Rh2
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Ginsenoside Rh2
| InChIKey | CKUVNOCSBYYHIS-IRFFNABBSA-N |
New Products
Dexamethasone Sodium Phosphate 2-(2-Ethoxyphenoxy)ethyl bromide 8-Bromo-7-(2-butynyl)-3-methyl xanthine 5-Chlorothiophene-2-carboxylic acid m-Tolualdehyde p-Anisaldehyde 2-Bromobenzaldehyde 4-Fluorobenzaldehyde 1-Propyl-4-piperidone 3-Amino-3-(3-fluorophenyl)propanoic acid 2-Fluoro-6-iodobenzoic acid 3-(4-Bromo-3-methyl-2-oxo-2,3-dihydro-1h-benzo[d]imidazol-1-yl)piperidine-2,6-dione 2,3-Dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-1H-inden-1-one hydrochloride ethyl 2-oxo-2,3,9,10-tetrahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline-8(7H)-carboxylate 1-Boc-4-cyanopiperidine 3-Pyridineacrylic acid Abiraterone Ethyl Ether Vardenafil Bis-sulphonamide(Dimer) 1-nitro-3,5-dimethyl adamantine (NMEM) 3-(2-aminoethyl) benzene sulfonamide Nabumetone Impurity 5 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-one 2-Amino-3,5-Dichloro-4-picoline 5-Amino-2-EthoxypyridineRelated products of tetrahydrofuran
You may like
-
Ginsenoside Rh2 CAS 78214-33-2View Details
78214-33-2 -
141-30-0 3,6-Dichloropyridazine 98%View Details
141-30-0 -
Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 27143-07-3 98%View Details
27143-07-3 -
94-71-3 98%View Details
94-71-3 -
Methyl 2-methoxy-5-sulfamoylbenzoate 33045-52-2 98%View Details
33045-52-2 -
3,6-Dichloro-4-Isopropylpyridazine 107228-51-3 98%View Details
107228-51-3 -
4640-67-9 98%View Details
4640-67-9 -
2-[(2-Ethoxyphenoxy)methyl]oxirane 98%View Details
5296-35-5