GERANYLGERANIOL

Chemical properties

Light Yellow Oil

The Uses of GERANYLGERANIOL

Geranylgeraniol, a precursor to Geranylgeranylpyrophosphate (G367600), is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-adsorption, inhibition of osteocl ast formation, and kinase activation in vitro.

The Uses of GERANYLGERANIOL

A intermediate in the lipidation of proteins, which plays a great importance for a variety of biological processes such as cell signalling

The Uses of GERANYLGERANIOL

Geranylgeraniol, a precursor to Geranylgeranylpyrophosphate (G367600), is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-adsorption, inhibition of osteoclast formation, and kinase activation in vitro.

What are the applications of Application

Geranylgeraniol is an intermediate in the mevalonate pathway, shown to prevent bone-reabsorption and inhibit osteoclast formation.

Definition

ChEBI: Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.

Biochem/physiol Actions

As the pyrophosphate, the metabolic precursor of all diterpenes. Screening in vitro shows this to be a potent and selective agent against Mycobacterium tuberculosis.