GDC-0810(ARN-810)
- CAS NO.：1365888-06-7
- Empirical Formula: C26H20ClFN2O2
- Molecular Weight: 446.9
- MDL number: MFCD28902190
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is GDC-0810(ARN-810)?
The Uses of GDC-0810(ARN-810)
Brilanestrant is an orally bioavailable Selective Estrogen Receptor Degrader (SERD) that demonstrates robust activity in tamoxifen-resistant breast cancer xenografts. GDC-0810 functions by binding to the estrogen receptor, inducing a conformational change resulting in the degradation of the receptor. GDC-0810 or ARN-810 demonstrates robust activity in models of tamoxifen-sensitive and tamoxifen-resistant breast cancer, and is currently in clinical trials in women with locally advanced or metastatic estrogen receptor-positive breast cancer.
Properties of GDC-0810(ARN-810)
| Boiling point: | 622.8±55.0 °C(Predicted) |
| Density | 1.342±0.06 g/cm3(Predicted) |
| solubility | DMSO:89.0(Max Conc. mg/mL);199.15(Max Conc. mM) Ethanol:89.0(Max Conc. mg/mL);199.15(Max Conc. mM) |
| form | A solid |
| pka | 13.94±0.40(Predicted) |
| color | White to off-white |
Safety information for GDC-0810(ARN-810)
Computed Descriptors for GDC-0810(ARN-810)
New Products
2-(2-Chlorophenyl)glycine Propiolic Acid 1-(3-Hydroxy-4-methoxyphenyl)-2-nitroethene (±)-amino(2-fluorophenyl)acetic acid trans-3-Benzyloxy-4-methoxy-beta-nitrostyrene 1-Pentadecanol 2,4-Dihydroxybenzaldehyde Dipropyl disulfide Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Obidoxime hydrochloride API 4 pentyn 1 ol N-Vinylformamide Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. 2-Pentyn-1-oL 4-NitrobenzotrifluorideRelated products of tetrahydrofuran
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