GANGLIOSIDE GD1A DISODIUM SALT
Synonym(s):Disialoganglioside-GD1a (porcine brain, diammonium salt);Ganglioside GD1a, disialo from bovine brain
- CAS NO.：12707-58-3
- Empirical Formula: C84H146N4Na2O39
- Molecular Weight: 1882.04098
- MDL number: MFCD00130960
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 09:27:42
What is GANGLIOSIDE GD1A DISODIUM SALT?
Description
Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver. It can be shed from the surface of tumor cells into the microenvironment where it influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis. Ganglioside GD1a (20 μM) also increases endothelial cell proliferation. Furthermore, ganglioside GD1a has been shown to act as a functional coreceptor for toll-like receptor 2 (TLR2), enabling the recruitment of TLR2 to lipid rafts when bound by a bacterial toxin. Ganglioside GD1a mixture contains ganglioside GD1a molecular species with C18:1 and C20:1 sphingoid backbones.
Chemical properties
White powder
The Uses of GANGLIOSIDE GD1A DISODIUM SALT
Ganglioside GD1a Disodium Salt is an agent with a stimulatory effect on phagocytosis and phagosome-lysosome.
What are the applications of Application
Ganglioside GD1a disodium salt is an agent with a stimulatory effect on phagocytosis and phagosome-lysosome
General Description
Ganglioside GD1a is an anionic brain ganglioside. It is localized in the inner and outer membrane of nuclear envelope of the neuronal cells. GD1a contains a neutral tetrasaccharide core, with one or two sialic acid on the internal galactose. It also has an additional sialic acid on the non-reducing terminal of galactose.
Properties of GANGLIOSIDE GD1A DISODIUM SALT
| storage temp. | -20°C |
| solubility | DMSO: soluble |
| form | lyophilized powder |
| BRN | 6228822 |
Safety information for GANGLIOSIDE GD1A DISODIUM SALT
Computed Descriptors for GANGLIOSIDE GD1A DISODIUM SALT
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