gamma-Benzyl L-glutamate
Synonym(s):L -Glutamic acid 5-benzyl ester
- CAS NO.：1676-73-9
- Empirical Formula: C12H15NO4
- Molecular Weight: 237.25
- MDL number: MFCD00002633
- EINECS: 216-826-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-10-23 14:42:30
What is gamma-Benzyl L-glutamate?
Chemical properties
white powder
The Uses of gamma-Benzyl L-glutamate
L-Glutamic acid γ-benzyl ester is commonly used in the synthesis of polymers for biological applications. Some of the examples are:
- Synthesis of bioreducible block copolymers based on poly(ethylene glycol) and poly(γ-benzyl L-glutamate) for Intracellular drug delivery.
- Synthesis of biodegradable poly(L-glutamic acid)-b-polylactide for magnetic resonance imaging (MRI)-visible drug delivery system.
- Synthesis of pH and temperature-responsive diblock copolymers based on poly(L-glutamic acid).
Purification Methods
Recrystallise the ester from H2O and store it at 0o. [Estrin Biochemical Preparations 13 25 1971, Beilstein 6 IV 2538.]
Properties of gamma-Benzyl L-glutamate
| Melting point: | 181-182 °C(lit.) |
| Boiling point: | 379.78°C (rough estimate) |
| alpha | 27.2 º (c=2, 1N HCL) |
| Density | 1.2026 (rough estimate) |
| refractive index | 1.5200 (estimate) |
| storage temp. | 2-8°C |
| solubility | Acetic Acid (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated) |
| form | Powder |
| pka | 2.20±0.10(Predicted) |
| color | White |
| optical activity | [α]20/D +19±2°, c = 1% in acetic acid |
| BRN | 1885646 |
| CAS DataBase Reference | 1676-73-9(CAS DataBase Reference) |
| EPA Substance Registry System | L-Glutamic acid, 5-(phenylmethyl) ester (1676-73-9) |
Safety information for gamma-Benzyl L-glutamate
Computed Descriptors for gamma-Benzyl L-glutamate
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