Gallic acid
Synonym(s):3,4,5-Trihydroxybenzoic acid;Gallic acid
- CAS NO.:149-91-7
- Empirical Formula: C7H6O5
- Molecular Weight: 170.12
- MDL number: MFCD00002510
- EINECS: 205-749-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-28 19:59:05
What is Gallic acid?
Description
Gallic acid is a tri hydroxy benzoic acid, a type of phenolic acid, a type of organic acid, also known as 3,4,5- tri hydroxy benzoic acid, found in gallnuts, sumac, witch hazel, tea leaves, oak bark, and other plants. The chemical formula is C6H2(OH)3COOH. Gallic acid is found both free and as part of hydrolyzable tannins.
Salts and esters of gallic acid are termed 'gallates'. Despite its name, it does not contain gallium.
Gallic acid is commonly used in the pharmaceutical industry. It is used as a standard for determining the phenol content of various analytes by the Folin - Ciocalteau assay; results are reported in gallic acid equivalents. Gallic acid can also be used as a starting material in the synthesis of the psychedelic alkaloid mescaline.
Gallic acid seems to have anti-fungal and anti - viral properties. Gallic acid acts as an antioxidant and helps to protect human cells against oxidative damage. Gallic acid was found to show cytotoxicity against cancer cells, without harming healthy cells. Gallic acid is used as a remote astringent in cases of internal haemorrhage. Gallic acid is also used to treat albuminuria and diabetes. Some ointments to treat psoriasis and external haemorrhoids contain gallic acid.
Description
Gallic Acid, or 3,4,5-trihydroxybenzoic acid, is produced by plants such as sumac, tea leaves, oak bark, and witch hazel; it provides the astringent property and antihemorrhoid activity of witch hazel. Derivatives are used in the production of azo dyes and photographic developers. It gets its name from gall nuts, which are the swelling of plant tissue in response to parasitic infection.
The Uses of Gallic acid
Gallic acid is a trihydroxybenzoic acid found in many plants as either the free acid or in the esterified form of gallotannins and ellagitannins. It demonstrates antioxidant activity by scavenging 2,2-diphenyl-1-picrylhydrazyl and hydroxyl free radicals with IC50 values of 9.4 and 191 μM, respectively, and inhibiting microsomal lipid peroxidation with an IC50 value of 1.51 μM. Gallic acid is often used as a standard for determining the phenol content of various analytes by the Folin-Ciocalteau assay where results are reported in gallic acid equivalents.[Cayman Chemical]
What are the applications of Application
Gallic acid is a cyclooxygease inhibitor substance found in plants
Properties of Gallic acid
Melting point: | 251 °C (dec.) (lit.) |
Boiling point: | 259.73°C (rough estimate) |
Density | 1.694 |
storage temp. | 2-8°C |
solubility | Methanol (Slightly), Water (Slightly, Heated) |
form | Powder |
color | Off-white |
Water Solubility | 12 g/L cold water |
Safety information for Gallic acid
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Gallic acid
InChIKey | LNTHITQWFMADLM-UHFFFAOYSA-N |
Abamectin manufacturer
Jigs Chemical ltd
Ralington Pharma
Twinkle Chemi Lab Pvt Ltd
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