Gaboxadol hydrochloride

The Uses of Gaboxadol hydrochloride

Gaboxadol hydrochloride has been used in cell migration and invasion assay to assess liver cancer cell migration.

The Uses of Gaboxadol hydrochloride

GABAergic Agonist

The Uses of Gaboxadol hydrochloride

Gaboxadol is a sleep aid drug used for the treatment of chronic pain and insomnia. Gaboxadol is also known to exhibit antidepressant like properties through its agonistic activities towards GABA sites .

The Uses of Gaboxadol hydrochloride

As a molecular probe to study GABA receptors.

General Description

Gaboxadol, also referred to as 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP), is a GABA site agonist. It has great affinity to the δ subunit of extrasynaptic high-affinity GABAA receptors. Gaboxadol was first developed for the treatment of schizophrenia, epilepsy, primary insomnia and Huntington′s disease. It can easily cross the blood-brain barrier and is rapidly absorbed by the body.

Biochem/physiol Actions

GABAA receptor agonist.

Storage

Store at RT