FR 900098 MonosodiuM Salt

Synonym(s):(3-(Acetylhydroxyamino)propyl)-phosphonic acid;BRN 2096083;P-[3-(Acetylhydroxyamino)propyl]-phosphonic acid

CAS NO.：73226-73-0
Empirical Formula: C5H11NNaO5P
Molecular Weight: 219.108071
MDL number: MFCD17215926
SAFETY DATA SHEET (SDS)
Update Date: 2026-04-24 14:58:07

What is FR 900098 MonosodiuM Salt?

Chemical properties

Pale Brown Solid

The Uses of FR 900098 MonosodiuM Salt

The antibiotics Fosmidomycin and FR900098 are members of a unique class of phosphonic acid natural products that inhibit the nonmevalonate pathway for isoprenoid biosynthesis. Both are potent antibacterial and antimalarial compounds.

What are the applications of Application

FR 900098 Monosodium Salt is a member of a unique class of phosphonic acid natural products

Biochem/physiol Actions

1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is an enzyme involved in the first step in the nonmevalonate pathway for isoprenoid biosynthesis in Gram-negative, Gram-positive bacteria, plants, and the parasite causing the most virulent form of malaria, Plasmodium falciparum (Mammals produce isoprenoids via the mevalonate pathway). Inhibiton of the enzyme provides alternative to traditional antimalaria therapy. FR-900098 is twice more effective than fosmidomycin against various strains of P. falciparum in vitro and the closely related P. vinckei in mice.

Properties of FR 900098 MonosodiuM Salt

Melting point:	184-186°C
storage temp.	-20°C
solubility	H2O: ≥20mg/mL
form	powder
color	white to light brown
Stability:	Hygroscopic

Safety information for FR 900098 MonosodiuM Salt

Computed Descriptors for FR 900098 MonosodiuM Salt

New Products

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