FR 139317
- CAS NO.：142375-60-8
- Empirical Formula: C33H44N6O5
- Molecular Weight: 604.74
- MDL number: MFCD00467722
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 10:31:43
What is FR 139317?
The Uses of FR 139317
FR 139317 is a novel, potent endothelin ETA receptor antagonist.
Biological Activity
A highly potent and selective ET A endothelin receptor antagonist (K i values are 1 nM and 7.3 μ M at ET A and ET B subtypes respectively). Active in vivo .
Properties of FR 139317
| Boiling point: | 943.9±65.0 °C(Predicted) |
| Density | 1.27±0.1 g/cm3(Predicted) |
| storage temp. | Desiccate at +4°C |
| solubility | Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO |
| form | Powder |
| pka | 2.68±0.10(Predicted) |
Safety information for FR 139317
Computed Descriptors for FR 139317
New Products
3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Pentadecanoic acid Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 5-Bromo-2-Fluoropyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4-Bromo-3-(ethoxymethyl)benzoic acid 2,4-Dichloro-5-methoxyaniline 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine N2-Isobutyryl-2'-O-methylguanosine 2-chloro-5-methylpyridin-4-amine 4-Bromobenzaldehyde 2-Chloro-6-nitro benzothiazole 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amineRelated products of tetrahydrofuran
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