FR 139317
- CAS NO.：142375-60-8
- Empirical Formula: C33H44N6O5
- Molecular Weight: 604.74
- MDL number: MFCD00467722
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is FR 139317?
The Uses of FR 139317
FR 139317 is a novel, potent endothelin ETA receptor antagonist.
Biological Activity
A highly potent and selective ET A endothelin receptor antagonist (K i values are 1 nM and 7.3 μ M at ET A and ET B subtypes respectively). Active in vivo .
Properties of FR 139317
| Boiling point: | 943.9±65.0 °C(Predicted) |
| Density | 1.27±0.1 g/cm3(Predicted) |
| storage temp. | Desiccate at +4°C |
| solubility | Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO |
| form | Powder |
| pka | 2.68±0.10(Predicted) |
Safety information for FR 139317
Computed Descriptors for FR 139317
New Products
2-(2-Chlorophenyl)glycine Propiolic Acid 1-(3-Hydroxy-4-methoxyphenyl)-2-nitroethene (±)-amino(2-fluorophenyl)acetic acid trans-3-Benzyloxy-4-methoxy-beta-nitrostyrene 1-Pentadecanol 4-(4-Αminophenyl)-3-Morpholinone 3-Morpholino-1-(4-(2-oxopiperidin-1-yl) phenyl)-5,6-dihyropyridin-2-(1H)-one 1-(4-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one N-cyanoacetylurethane 1H-IndazoleRelated products of tetrahydrofuran
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