FPL 64176
Synonym(s):2,5-Dimethyl-4-[2-(phenylmethyl)benzoyl]-1H-pyrrole-3-carboxlic acid methyl ester
- CAS NO.：120934-96-5
- Empirical Formula: C22H21NO3
- Molecular Weight: 347.41
- MDL number: MFCD00274043
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 10:31:43
What is FPL 64176?
The Uses of FPL 64176
FPL-64176 is a nondihydropyridine Ca2+ channel activator.
What are the applications of Application
FPL-64176 is a nondihydropyridine Ca2+ channel activator
Definition
ChEBI: FPL 64176 is 1H-Pyrrole substituted at C-2 and -5 by methyl groups, at C-3 by methoxycarbonyl and at C-4 by a 2-benzylbenzoyl group. It has a role as a calcium channel agonist. It is a member of pyrroles and a carboxylic ester.
Biological Activity
Potent activator of L-type Ca 2+ channels (EC 50 = 16 nM). 40-fold more potent than Bay K 8644 (1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester ) as a positive inotrope in guinea pig atria.
Biochem/physiol Actions
Potent Ca2+ channel (L-type) activator.
Storage
Store at RT
Properties of FPL 64176
| storage temp. | 2-8°C |
| solubility | DMSO: 10 mg/mL Solutions should be freshly prepared. |
| form | solid |
| color | tan |
Safety information for FPL 64176
Computed Descriptors for FPL 64176
New Products
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