FPL 64176
Synonym(s):2,5-Dimethyl-4-[2-(phenylmethyl)benzoyl]-1H-pyrrole-3-carboxlic acid methyl ester
- CAS NO.：120934-96-5
- Empirical Formula: C22H21NO3
- Molecular Weight: 347.41
- MDL number: MFCD00274043
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-16 07:06:08
What is FPL 64176?
The Uses of FPL 64176
FPL-64176 is a nondihydropyridine Ca2+ channel activator.
What are the applications of Application
FPL-64176 is a nondihydropyridine Ca2+ channel activator
Definition
ChEBI: FPL 64176 is 1H-Pyrrole substituted at C-2 and -5 by methyl groups, at C-3 by methoxycarbonyl and at C-4 by a 2-benzylbenzoyl group. It has a role as a calcium channel agonist. It is a member of pyrroles and a carboxylic ester.
Biological Activity
Potent activator of L-type Ca 2+ channels (EC 50 = 16 nM). 40-fold more potent than Bay K 8644 (1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester ) as a positive inotrope in guinea pig atria.
Biochem/physiol Actions
Potent Ca2+ channel (L-type) activator.
Storage
Store at RT
Properties of FPL 64176
| storage temp. | 2-8°C |
| solubility | DMSO: 10 mg/mL Solutions should be freshly prepared. |
| form | solid |
| color | tan |
Safety information for FPL 64176
Computed Descriptors for FPL 64176
New Products
5-bromo-4-fluoro-2-nitrobenzaldehyde Cyclobutanone (R)-(-)-2-Amino-1-propanol Fmoc-OSu 1-(2-Chloroethyl)pyrrolidine Hydrochloride 2-Amino-2-(4-methylphenyl)acetic acid 2,4-Dihydroxybenzaldehyde Obidoxime hydrochloride API Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Dipropyl disulfide 4 pentyn 1 ol N-Vinylformamide Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL 2-Pentyn-1-oL 4-Nitrobenzotrifluoride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd.Related products of tetrahydrofuran
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