Forodesine
- CAS NO.：1191450-19-7
- Empirical Formula: C27H52BrN8O3P
- Molecular Weight: 647.64
- MDL number: MFCD31813774
- Update Date: 2026-08-05 09:01:00
What is Forodesine?
Description
Burixafor, also known as TG-0054, is an orally bioavailable inhibitor of CXC chemokine receptor 4 (CXCR4) with receptor binding and hematopoietic stem cell-mobilization activities. Burixafor binds to the chemokine receptor CXCR4, thereby preventing the binding of stromal derived factor-1 (SDF-1 or CXCL12) to the CXCR4 receptor and subsequent receptor activation; this may the mobilization of hematopoietic stem and progenitor cells from the bone marrow into blood. Note: Elemental analysis showed it was a salt with 3 HBr and 3 water.
Properties of Forodesine
| storage temp. | Store at -20°C |
| form | Solid |
| color | Light yellow to yellow |
| Water Solubility | Water : 50 mg/mL |
Safety information for Forodesine
Computed Descriptors for Forodesine
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