Fmoc-N-methyl-L-aspartic acid 4-tert-butyl ester
Synonym(s):N-Methyl aspartic acid;Fmoc-N-Me-Asp(OtBu)-OH;N-α-Fmoc-N-α-methyl-L-aspartic acid β-tert butyl ester
- CAS NO.：152548-66-8
- Empirical Formula: C24H27NO6
- Molecular Weight: 425.48
- MDL number: MFCD00237027
- EINECS: 240-880-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-02 22:15:05
What is Fmoc-N-methyl-L-aspartic acid 4-tert-butyl ester?
Chemical properties
White to off-white solid
The Uses of Fmoc-N-methyl-L-aspartic acid 4-tert-butyl ester
Fmoc protected N-methyl amino acid suitable for solid phase peptide synthesis. N-methyl amino acids have been shown to improve proteolytic stability of peptides.
Properties of Fmoc-N-methyl-L-aspartic acid 4-tert-butyl ester
| Melting point: | 135-140°C |
| Boiling point: | 598.7±50.0 °C(Predicted) |
| Density | 1.237±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Soluble in water or 1% acetic acid |
| form | Powder |
| pka | 3.59±0.23(Predicted) |
| color | White to off-white |
| optical activity | [α]22/D -39.0°, c = 0.5% in DMF |
| CAS DataBase Reference | 152548-66-8(CAS DataBase Reference) |
Safety information for Fmoc-N-methyl-L-aspartic acid 4-tert-butyl ester
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Fmoc-N-methyl-L-aspartic acid 4-tert-butyl ester
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