FMOC-MET(O2)-OH

CAS NO.：163437-14-7
Empirical Formula: C20H21NO6S
Molecular Weight: 403.45
MDL number: MFCD00153361
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 00:19:14

What is FMOC-MET(O2)-OH?

Description

FMOC-Met (O2)-OH is the N-alpha protected form of L-methionine mediated by FMOC group (9-Fluorenylmethyloxycarbonyl). It is useful to act as a building block in peptide synthesis. For example, it, as well as its derivative Tbfmoc-Met-OH can be used as a building block for the solid phase synthesis of ubiquitin C-hydrazide. It can also be used for synthesizing some novel cyclic peptides with pharmacological effects such as treatment of inflammatory disease.

Chemical properties

White powder

References

http://www.sigmaaldrich.com/technical-documents/articles/chemfiles/natural-amino-acid.html
https://www.iris-biotech.de/de/faa1490/Anderson, S. N., et al. "Microarrayed compound screening (microARCS) to identify activators and inhibitors of AMP-activated protein kinase."Journal of Biomolecular Screening 9.2(2004):112-121.
http://web.b.ebscohost.com/abstract?direct=true&profile=ehost&scope=site&authtype=crawler&jrnl=09707077&AN=103358230&=iEFjDXbrcrGANWWK7vpLdmsN8yhCmNraNdm1aLMwCgXjuCpr9xSGhioVTsYZqXmo5JtrShPp2WNBkVHpx75ovQ%3d%3d&crl=c&resultNs=AdminWebAuth&resultLocal=ErrCrlNotAuth&crlhashurl=login.aspx%3fdirect%3dtrue%26profile%3dehost%26scope%3dsite%26authtype%3dcrawler%26jrnl%3d09707077%26AN%3d103358230
http://www.google.com/patents/US6511961

Properties of FMOC-MET(O2)-OH

Boiling point:	709.5±60.0 °C(Predicted)
Density	1.359
storage temp.	Sealed in dry,Room Temperature
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka	3.52±0.10(Predicted)
form	Powder
color	White
CAS DataBase Reference	163437-14-7(CAS DataBase Reference)