Fmoc-L-photo-methionine
Synonym(s):(S)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)-4-(3-methyl-3H-diazirin-3-yl)butanoic acid;(S)-2-(Fmoc-amino)-4-(3H-diazirin-3-yl)pentanoic acid;Diazirine amino acid;Photo-crosslinking amino acid;Photo-Met
- CAS NO.：945859-89-2
- Empirical Formula: C21H21N3O4
- Molecular Weight: 379.42
- MDL number: MFCD31380717
- Update Date: 2026-04-24 14:58:42
What is Fmoc-L-photo-methionine?
The Uses of Fmoc-L-photo-methionine
Fmoc-L-photo-methionine is a diazirine-containing, Fmoc-protected methionine amino acid and multifunctional photo-crosslinker. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (～360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An unprotected version is also available as 907375.
Properties of Fmoc-L-photo-methionine
| Density | 1.38±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| pka | 3.83±0.10(Predicted) |
Safety information for Fmoc-L-photo-methionine
Computed Descriptors for Fmoc-L-photo-methionine
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