Fmoc-Phe-OH
Synonym(s):N-(9-Fluorenylmethoxycarbonyl)-L -phenylalanine;Fmoc-L -phenylalanine;Fmoc-Phe-OH;N-α-Fmoc-L-phenylalanine
- CAS NO.：35661-40-6
- Empirical Formula: C24H21NO4
- Molecular Weight: 387.43
- MDL number: MFCD00037128
- EINECS: 252-661-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is Fmoc-Phe-OH?
Chemical properties
white to light yellow crystal powde
The Uses of Fmoc-Phe-OH
(Fmoc-Phe-OH) L-Phenylalanine (P319415) derivative, used in the preparation of peptides and deltorphin derivatives. A potential inhibitor of IGF-I and IGF-Binding Protein-5 complex.
General Description
Fmoc-Phe-OH is highly hydrophobic and dissolves easily in DMF and NMP. A photoresponsive hydrogel can be easily created by co-assembling Fmoc-Phe-OH and Azp without the need for chemical synthesis.
Properties of Fmoc-Phe-OH
| Melting point: | 180-187 °C(lit.) |
| Boiling point: | 513.39°C (rough estimate) |
| alpha | -38 º (c=1,DMF) |
| Density | 1.2379 (rough estimate) |
| refractive index | -39.5 ° (C=1, DMF) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), DMF (Sparingly, Sonicated), DMSO (Slightly) |
| form | Powder |
| pka | 3.77±0.10(Predicted) |
| color | White |
| optical activity | [α]20/D 37°, c = 1 in DMF |
| BRN | 3597808 |
| InChI | InChI=1S/C24H21NO4/c26-23(27)22(14-16-8-2-1-3-9-16)25-24(28)29-15-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h1-13,21-22H,14-15H2,(H,25,28)(H,26,27)/t22-/m0/s1 |
| CAS DataBase Reference | 35661-40-6(CAS DataBase Reference) |
Safety information for Fmoc-Phe-OH
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H413:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Fmoc-Phe-OH
| InChIKey | SJVFAHZPLIXNDH-QFIPXVFZSA-N |
| SMILES | C(O)(=O)[C@H](CC1=CC=CC=C1)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O |
Fmoc-Phe-OH manufacturer
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