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HomeProduct name listFlutrimazole

Flutrimazole

Synonym(s):1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole

Flutrimazole Structural

What is Flutrimazole?

Description

Flutrimazole, a novel imidazole antifungal launched in Spain, is indicated for mycosis of the skin. Flutrimazole displays potent broad-spectrum of activity against dematophytes, filamentous fungi and yeasts, saprophytic and pathogenic to animals and humans. Similar to other imidazole and triazole antifungals, flutrimazole exerts its biological function through inhibition of fungal lanosterol 14a-demethylase. Excellent local and systemic tolerance of flutrimazole in patients has been reported.

Chemical properties

White or almost white powder.

Originator

Uriach (Spain)

The Uses of Flutrimazole

Flutrimazole is a new imidazole antifungal agent with anti-inflammatory properties as well.

Definition

ChEBI: An imidazole antifungal agent that is imidazole in which the hydrogen attached to the nitrogen is replaced by a 2,4'-difluorotrityl group. A topical antifungal agent which displays potent broad-spectrum in vitro activity against dermatophytes, filamentous fungi and yeasts.

brand name

Micetal

Properties of Flutrimazole

Melting point: 161-166℃
Boiling point: 457.1±40.0 °C(Predicted)
Density  1.15±0.1 g/cm3(Predicted)
storage temp.  -20°C Freezer
solubility  Practically insoluble in water, freely soluble in tetrahydrofuran, soluble in methanol.
form  neat
pka 6.03±0.34(Predicted)
form  Solid
color  White to Pale Yellow
CAS DataBase Reference 119006-77-8(CAS DataBase Reference)

Safety information for Flutrimazole

Computed Descriptors for Flutrimazole

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