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HomeProduct name listFLURBIPROFEN-D3

FLURBIPROFEN-D3

FLURBIPROFEN-D3 Structural

What is FLURBIPROFEN-D3?

Description

Flurbiprofen-d3 is intended for use as an internal standard for the quantification of flurbiprofen (Item Nos. 70250 | 10004207 | 70255) by GC- or LC-MS. Flurbiprofen is a non-selective COX inhibitor (IC50s = 0.04 and 0.51 μM for COX-1 and COX-2, respectively). In vivo, flurbiprofen (0.3-4.8 mg/kg, p.o.) reduces carrageenan-induced hind paw edema and yeast-induced fever in rats. Flurbiprofen reduces plasma fibrinogen levels and arthritic score in a rat model of adjuvant-induced arthritis. It also reduces tumor weight and prostaglandin production and increases survival in a WHT-NC mouse xenograft model when administered at a dose of 5 mg/kg. Formulations containing flurbiprofen have been used to manage pain and inflammation associated with arthritis.

Chemical properties

White Solid

The Uses of FLURBIPROFEN-D3

An Isotopically labeled analog of Flurbiprofe

The Uses of FLURBIPROFEN-D3

An isotopically labelled analog of Flurbiprofen (F598700).

What are the applications of Application

Flurbiprofen-d3 is an isotopically labelled analog of Flurbiprofen

Properties of FLURBIPROFEN-D3

Melting point: 108-110°C
storage temp.  -20°C Freezer
solubility  DMF: 25 mg/ml,DMSO: 10 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 0.9 mg/ml
form  A solid
color  White to off-white

Safety information for FLURBIPROFEN-D3

Computed Descriptors for FLURBIPROFEN-D3

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