Fluprostenol
Synonym(s):(±)-16-(3-Trifluoromethylphenoxy)tetranorprostaglandin F2α
- CAS NO.：40666-16-8
- Empirical Formula: C23H29F3O6
- Molecular Weight: 458.47
- MDL number: MFCD03427566
- EINECS: 255-029-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:21
What is Fluprostenol?
The Uses of Fluprostenol
Fluprostenol is a prostaglandin F (FP) receptor agonist.
What are the applications of Application
Fluprostenol is a prostaglandin F (FP) receptor agonist
Definition
ChEBI: Fluprostenol is an organofluorine compound that is racemic prostaglandin F2alpha in which the pentyl group is replaced by a 3-(trifluoromethyl)phenoxymethyl group. A synthetic analogue of prostaglandin F2alpha, ophthalmic solutions of its isopropyl ester prodrug, travoprost, are used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. The isopropyl ester group of travoprost is hydrolysed to the biologically active free acid by esterases in the cornea. It has a role as an antiglaucoma drug, an antihypertensive agent, a prostaglandin receptor agonist, a female contraceptive drug and an abortifacient. It is a prostaglandins Falpha, a hydroxy monocarboxylic acid and a member of (trifluoromethyl)benzenes.
Properties of Fluprostenol
| Boiling point: | 608.0±55.0 °C(Predicted) |
| Density | 1.335 |
| storage temp. | −20°C |
| form | Colorless oil dissolved in ethanol (1mg/100μl). |
| pka | 4.76±0.10(Predicted) |
Safety information for Fluprostenol
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H225:Flammable liquids H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Fluprostenol
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