Flecainide hydrochloride

CAS NO.：57415-44-8
Empirical Formula: C17H21ClF6N2O3
Molecular Weight: 450.81
MDL number: MFCD19982476
SAFETY DATA SHEET (SDS)
Update Date: 2026-07-16 07:06:08

What is Flecainide hydrochloride?

Biological Activity

Flecainide hydrochloride is a potent and orally active antiarrhythmic agent. Flecainide hydrochloride blocks the cardiac fast inward Na+ current (INa) and the rapid component of the delayed rectifier K+ current. Flecainide hydrochloride prolongs the action potential duration (APD) in ventricular and atrial muscle fibres. Flecainide hydrochloride has the potential for the research of fetal tachycardias[1][2][3].

References

[1]. Echt DS, et al. Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial. N Engl J Med. 1991 Mar 21;324(12):781-8.[2]. Aliot E, et al. Twenty-five years in the making: flecainide is safe and effective for the management of atrial fibrillation. Europace. 2011 Feb;13(2):161-73.[3]. Allan LD, et al. Flecainide in the treatment of fetal tachycardias. Br Heart J. 1991 Jan;65(1):46-8.

Properties of Flecainide hydrochloride

storage temp.	Store at -20°C
form	Solid
color	White to off-white

Safety information for Flecainide hydrochloride

Computed Descriptors for Flecainide hydrochloride

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