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HomeProduct name listFL118

FL118

FL118 Structural

What is FL118?

The Uses of FL118

(R)-FL-118 is a derivative of Camptothecin (C175150), which is antitumor alkaloid that binds to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I, trapping the enzyme in a covalent linkage with DNA.

Properties of FL118

Boiling point: 812.1±65.0 °C(Predicted)
Density  1?+-.0.1 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  DMSO : 2.7 mg/mL (6.88 mM; ultrasonic and warming and heat to 60°C)
pka 11.18±0.20(Predicted)
form  Solid
color  Off-white to yellow

Safety information for FL118

Computed Descriptors for FL118

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