FGTI-2734

CAS NO.：1247018-19-4
Empirical Formula: C26H31FN6O2S
Molecular Weight: 510.63
MDL number: MFCD32174296
Update Date: 2026-06-03 11:24:09

What is FGTI-2734?

Description

FGTI-2734 is a RAS C-terminal mimetic dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor. It can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors.

Properties of FGTI-2734

Boiling point:	770.1±70.0 °C(Predicted)
Density	1.28±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO:50.0(Max Conc. mg/mL);97.92(Max Conc. mM)
form	Solid
pka	6.60±0.10(Predicted)
color	White to off-white

Safety information for FGTI-2734

Computed Descriptors for FGTI-2734

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