FGIN-1-27
Synonym(s):FGIN-1-27
- CAS NO.：142720-24-9
- Empirical Formula: C28H37FN2O
- Molecular Weight: 436.6
- MDL number: MFCD00467704
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-27 08:46:37
What is FGIN-1-27?
Chemical properties
white to off-white powder
The Uses of FGIN-1-27
FGIN-1-27 is a potent inositol monophosphatase inhibitor.
What are the applications of Application
FGIN-1-27 is a potent inositol monophosphatase inhibitor
Definition
ChEBI: 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide is a phenylindole.
Biological Activity
Binds specifically and with high affinity to the peptide DBI receptor (benzodiazepine receptor) on mitochondrial membranes, inducing production of neurosteroids, which modulate GABA receptors (EC 50 = 3 nM for increase in production of pregnenolone in glial cells). Thus it reduces anxiety without causing sedation.
Storage
Room temperature
Properties of FGIN-1-27
| Melting point: | 96-97 °C |
| Boiling point: | 608.3±55.0 °C(Predicted) |
| Density | 1.0538 (estimate) |
| storage temp. | 2-8°C |
| solubility | methanol: 20 mg/mL |
| form | White powder. |
| pka | 16.45±0.30(Predicted) |
| color | Off-white to light yellow |
Safety information for FGIN-1-27
Computed Descriptors for FGIN-1-27
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