FGIN-1-27
Synonym(s):FGIN-1-27
- CAS NO.：142720-24-9
- Empirical Formula: C28H37FN2O
- Molecular Weight: 436.6
- MDL number: MFCD00467704
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-14 16:49:18
What is FGIN-1-27?
Chemical properties
white to off-white powder
The Uses of FGIN-1-27
FGIN-1-27 is a potent inositol monophosphatase inhibitor.
What are the applications of Application
FGIN-1-27 is a potent inositol monophosphatase inhibitor
Definition
ChEBI: 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide is a phenylindole.
Biological Activity
Binds specifically and with high affinity to the peptide DBI receptor (benzodiazepine receptor) on mitochondrial membranes, inducing production of neurosteroids, which modulate GABA receptors (EC 50 = 3 nM for increase in production of pregnenolone in glial cells). Thus it reduces anxiety without causing sedation.
Storage
Room temperature
Properties of FGIN-1-27
| Melting point: | 96-97 °C |
| Boiling point: | 608.3±55.0 °C(Predicted) |
| Density | 1.0538 (estimate) |
| storage temp. | 2-8°C |
| solubility | methanol: 20 mg/mL |
| form | White powder. |
| pka | 16.45±0.30(Predicted) |
| color | Off-white to light yellow |
Safety information for FGIN-1-27
Computed Descriptors for FGIN-1-27
New Products
9-Mesityl-10-methylacridinium perchlorate Sulfapyridine Fmoc-OSu (R)-(-)-2-Amino-1-propanol Cyclobutanone 5-bromo-4-fluoro-2-nitrobenzaldehyde 4 pentyn 1 ol N-Vinylformamide Phenethyl cinnamate Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Ethyl 3-phenylpropanoate β-Bromostyrene Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. 4-Nitrobenzotrifluoride 2-Pentyn-1-oL N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamideRelated products of tetrahydrofuran
![5-(4-METHOXYPHENYL)PYRROLO[2,1-D][1,5]BENZOTHIAZEPIN-4-OL ACETATE](https://img.chemicalbook.in/CAS/GIF/131403-76-4.gif)
![5-PHENYLPYRROLO[2,1-D][1,5]-BENZOTHIAZEPIN-4-OL HEXANOATE](https://img.chemicalbook.in/StructureFile/ChemBookStructure3/GIF/CB3669925.gif)
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