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HomeProduct name listFentonium

Fentonium

Fentonium Structural

What is Fentonium?

Originator

Hoelcesium,Zambon,Italy

Manufacturing Process

5.50g (0.02 mol) of p-phenylphenacyl bromide were dissolved in 56 cc of anhydrous acetone previously heated to about 40°C. This solution was added, with stirring, to a solution of 5.70 g (0.02 mol) of 1-hyoscyamine in 43 cc of anhydrous acetone; the reaction solution was maintained at 45°C and stirred for about six hours.
After standing overnight in the refrigerator, the precipitate was collected by filtration and dried in vacuo at 60°C. Yield: 10.2 g; MP = 193°C to 194°C.

Therapeutic Function

Anticholinergic, Spasmolytic

Properties of Fentonium

Melting point: 203-205° (dec); mp 193-194°
alpha  D23 -5.68° (c = 5 in DMF); D25 -4.7° (c = 5 in DMF)

Safety information for Fentonium

Computed Descriptors for Fentonium

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