FD 211
- CAS NO.：162341-24-4
- Empirical Formula: C13H16O4
- Molecular Weight: 236.26
- Update Date: 2023-05-21 10:59:17
What is FD 211?
Description
FD-211 is a δ lactone originally isolated from M. lutea with anticancer activity.1 It is cytotoxic to adriamycin-susceptible P388, T-24, HeLa, A549, and HL-60 cancer cells (IC50s = 4, 0.5, 1, 1, and 0.2 μg/ml, respectively), as well as adriamycin-resistant HL-60/ADR cells (IC50 = 0.1 μg/ml). FD-211 also inhibits DNA, RNA, and protein synthesis in HeLa cells (IC50 = 1.25 μg/ml for all).
References
1. Nozawa, O., Okazaki, T., Sakai, N., et al. A novel bioactive δ lactone FD-
Properties of FD 211
| Boiling point: | 442.3±45.0 °C(Predicted) |
| Density | 1.21±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Dichloromethane: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble |
| form | A crystalline solid |
| pka | 12.68±0.60(Predicted) |
Safety information for FD 211
Computed Descriptors for FD 211
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