Exifone

CAS NO.：52479-85-3
Empirical Formula: C13H10O7
Molecular Weight: 278.21
MDL number: MFCD00082966
EINECS: 257-945-9
SAFETY DATA SHEET (SDS)
Update Date: 2026-06-03 11:24:09

What is Exifone?

Description

Exifone is a nootropic indicated for the treatment of cognitive dysfunctions in geriatric patients. Its reported clinical efficacy is ascribed to pharmacological activities including activation of neuronal oxygen and glucose metabolism, free radical scavenging, and indirect effects on serotonergic and dopaminergic pathways.

Chemical properties

yellow amorphous powder

Originator

Pharmascience (France)

The Uses of Exifone

Exifone is a nootropic drug and cognitive enhancing agent. Exifone is a free radical scavenger shown to have protective effects againts Exifone has been shown to antagonize amnesias induced by benzodiazepines in mice.

Preparation

Preparation by condensation of gallic acid with pyrogallol,
? in the presence of zinc chloride at 120° (good yield) or at 145° for 3 h (Nencki reaction);
? in the presence of zinc chloride and phosphorous oxychloride at 80° for 2 h, via Fries rearrangement.

Definition

ChEBI: (2,3,4-trihydroxyphenyl)-(3,4,5-trihydroxyphenyl)methanone is a member of benzophenones.

brand name

Adlone

Properties of Exifone

Melting point:	245°C
Boiling point:	674.6±55.0 °C(Predicted)
Density	1.759±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	6.99±0.40(Predicted)
color	Yellow
Merck	3915
Stability:	Hygroscopic
CAS DataBase Reference	52479-85-3(CAS DataBase Reference)

Safety information for Exifone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to..…