Exalamide

Chemical properties

White Solid

Originator

Hyperan,S.S. Pharm,Japan,1980

The Uses of Exalamide

Exalamide is used as an antifungal (topical). Exalamide is a derivative of salicylamide.

What are the applications of Application

Exalamide is an antifungal agent

Definition

ChEBI: An arenecarboxamide that is salicylamide in which the phenolic hydroxy group has been converted to the corresponding hexyl ether. It has been used as a topical antifungal agent.

Manufacturing Process

4.6 g sodium were dissolved in 150 ml ethanol and 27.4 g (0.2 mol) salicylamide added. The solution was refluxed gently and 24.6 g (0.2mol) nhexyl- bromide added gradually. The mixture was refluxed for six hours, the precipitated sodium bromide filtered off, and most of the alcohol removed by distillation. Water was then added to the residue, and the 2-nhexyloxybenzamide filtered off. It crystallized from 50% aqueous ethanol in colorless crystals, MP 71°C.

Therapeutic Function

Antifungal