Exalamide
- CAS NO.：53370-90-4
- Empirical Formula: C13H19NO2
- Molecular Weight: 221.3
- MDL number: MFCD00865621
- EINECS: 258-504-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-21 16:37:02
What is Exalamide?
Chemical properties
White Solid
Originator
Hyperan,S.S. Pharm,Japan,1980
The Uses of Exalamide
Exalamide is used as an antifungal (topical). Exalamide is a derivative of salicylamide.
What are the applications of Application
Exalamide is an antifungal agent
Definition
ChEBI: An arenecarboxamide that is salicylamide in which the phenolic hydroxy group has been converted to the corresponding hexyl ether. It has been used as a topical antifungal agent.
Manufacturing Process
4.6 g sodium were dissolved in 150 ml ethanol and 27.4 g (0.2 mol) salicylamide added. The solution was refluxed gently and 24.6 g (0.2mol) nhexyl- bromide added gradually. The mixture was refluxed for six hours, the precipitated sodium bromide filtered off, and most of the alcohol removed by distillation. Water was then added to the residue, and the 2-nhexyloxybenzamide filtered off. It crystallized from 50% aqueous ethanol in colorless crystals, MP 71°C.
Therapeutic Function
Antifungal
Properties of Exalamide
| Melting point: | 72-74°C |
| Boiling point: | 362.36°C (rough estimate) |
| Density | 1.0451 (rough estimate) |
| refractive index | 1.5175 (estimate) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 15.62±0.50(Predicted) |
| color | White |
Safety information for Exalamide
Computed Descriptors for Exalamide
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