ETIROXATE
- CAS NO.：17365-01-4
- Empirical Formula: C18H17I4NO4
- Molecular Weight: 818.935
- MDL number: MFCD00865750
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:34
What is ETIROXATE?
Chemical properties
Tan Solid
Originator
Skleronorm,Gruenenthal,W. Germany,1977
The Uses of ETIROXATE
Derivative of thyroxine. Antilipemic
The Uses of ETIROXATE
Derivative of thyroxine. Antilipemic.
What are the applications of Application
Etiroxate is an antilipaemic derivative of thyroxine
Definition
ChEBI: Etiroxate is an aromatic ether.
Manufacturing Process
7.91 g of α-methyl thyroxine are suspended in 150 cc of ethanol. While heating, the solution is saturated with dry hydrogen chloride. Thereafter, the solvent is distilled off at reduced pressure. The residue is dissolved in a mixture of ethanol and water (1:1). Adding a 5% solution of sodium hydrogen carbonate in water, the ethyl ester of α-methyl thyroxine precipitates; melting point: 156°C to 157°C after recrystallization from ethanol. The yield is 6.05 g, i.e., 74% of the theoretical yield.
Therapeutic Function
Antihyperlipoproteinemic
Properties of ETIROXATE
| Melting point: | 149-1510C |
| Boiling point: | 563.7±50.0 °C(Predicted) |
| Density | 2.321±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMSO, Methanol |
| form | Solid |
| pka | 6.89±0.25(Predicted) |
| color | Tan |
Safety information for ETIROXATE
Computed Descriptors for ETIROXATE
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