Ethylthiourea
Synonym(s):1-Ethylthiourea
- CAS NO.：625-53-6
- Empirical Formula: C3H8N2S
- Molecular Weight: 104.17
- MDL number: MFCD00004939
- EINECS: 210-899-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:54:15
What is Ethylthiourea?
The Uses of Ethylthiourea
N-Ethylthiourea was used in the preparation of Re (III) complexes, which are precursors for the new rhenium complexes, potentially useful in nuclear medicine. It was also used in two-step protocol for the first chemoselective cleavage of 2-hydroxy acid amides
What are the applications of Application
Ethylthiourea is a bactericidal precursor
Definition
ChEBI: N-ethylthiourea is a member of the class of thioureas that is thiourea in which one of the hydrogens is replaced by an ethyl group. It is functionally related to a thiourea.
General Description
N-Ethylthiourea forms adduct with silver halides and their single crystal X-ray structural and spectroscopic characterizations are described.
Biological Activity
Potent, selective and reversible inhibitor of isoform II NO synthase (IC 50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively).
Safety Profile
Poison by ingestion. SYN: 1-ETHYLTHIOUREA Experimental teratogenic effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Sox and NOx.
Purification Methods
Crystallise the thiourea from EtOH, MeOH or ether. [Beilstein 4 IV 374.]
Properties of Ethylthiourea
| Melting point: | 108-110 °C(lit.) |
| Boiling point: | 132 °C |
| Density | 1.055 (estimate) |
| refractive index | 1.5500 (estimate) |
| storage temp. | Store at RT |
| solubility | methanol: soluble25mg/mL, clear, colorless |
| pka | 14.97±0.29(Predicted) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | Soluble in water (24g/L). |
| BRN | 1699551 |
| CAS DataBase Reference | 625-53-6(CAS DataBase Reference) |
| EPA Substance Registry System | Ethylthiourea (625-53-6) |
Safety information for Ethylthiourea
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral |
Computed Descriptors for Ethylthiourea
| InChIKey | GMEHFXXZSWDEDB-UHFFFAOYSA-N |
New Products
Cyclobutanone (R)-(-)-2-Amino-1-propanol Fmoc-OSu 5-bromo-4-fluoro-2-nitrobenzaldehyde 2-Amino-2-(4-methylphenyl)acetic acid 1-(2-Chloroethyl)pyrrolidine Hydrochloride 2,4-Dihydroxybenzaldehyde Obidoxime hydrochloride API Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Dipropyl disulfide N-Vinylformamide 4 pentyn 1 ol Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. 2-Pentyn-1-oL 4-Nitrobenzotrifluoride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamideRelated products of tetrahydrofuran
You may like
-
N-Ethylthiourea 98.00% CAS 625-53-6View Details
625-53-6 -
N-Ethylthiourea CAS 625-53-6View Details
625-53-6 -
7250-67-1 1-(2-Chloroethyl)pyrrolidine Hydrochloride 98+View Details
7250-67-1 -
13227-01-5 98+View Details
13227-01-5 -
545445-44-1 3-Morpholino-1-(4-(2-oxopiperidin-1-yl) phenyl)-5,6-dihyropyridin-2-(1H)-one 98%View Details
545445-44-1 -
6629-04-5 98%View Details
6629-04-5 -
4-(4-Αminophenyl)-3-Morpholinone 98%View Details
438056-69-0 -
1-(4-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one 1267610-26-3 98%View Details
1267610-26-3