ETHYLTHIOUREA
Synonym(s):1-Ethylthiourea
- CAS NO.：625-53-6
- Empirical Formula: C3H8N2S
- Molecular Weight: 104.17
- MDL number: MFCD00004939
- EINECS: 210-899-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-10 10:27:23
What is ETHYLTHIOUREA?
The Uses of ETHYLTHIOUREA
N-Ethylthiourea was used in the preparation of Re (III) complexes, which are precursors for the new rhenium complexes, potentially useful in nuclear medicine. It was also used in two-step protocol for the first chemoselective cleavage of 2-hydroxy acid amides
What are the applications of Application
Ethylthiourea is a bactericidal precursor
Definition
ChEBI: N-ethylthiourea is a member of the class of thioureas that is thiourea in which one of the hydrogens is replaced by an ethyl group. It is functionally related to a thiourea.
General Description
N-Ethylthiourea forms adduct with silver halides and their single crystal X-ray structural and spectroscopic characterizations are described.
Biological Activity
Potent, selective and reversible inhibitor of isoform II NO synthase (IC 50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively).
Safety Profile
Poison by ingestion. SYN: 1-ETHYLTHIOUREA Experimental teratogenic effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Sox and NOx.
Purification Methods
Crystallise the thiourea from EtOH, MeOH or ether. [Beilstein 4 IV 374.]
Properties of ETHYLTHIOUREA
| Melting point: | 108-110 °C(lit.) |
| Boiling point: | 132 °C |
| Density | 1.055 (estimate) |
| refractive index | 1.5500 (estimate) |
| storage temp. | Store at RT |
| solubility | methanol: soluble25mg/mL, clear, colorless |
| pka | 14.97±0.29(Predicted) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | Soluble in water (24g/L). |
| BRN | 1699551 |
| CAS DataBase Reference | 625-53-6(CAS DataBase Reference) |
| EPA Substance Registry System | Ethylthiourea (625-53-6) |
Safety information for ETHYLTHIOUREA
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral |
Computed Descriptors for ETHYLTHIOUREA
| InChIKey | GMEHFXXZSWDEDB-UHFFFAOYSA-N |
New Products
2-(2-Ethoxyphenoxy)ethyl bromide 1,3-Dibromo-2,2-dimethoxypropane 8-Bromo-7-(2-butynyl)-3-methyl xanthine 5-Chlorothiophene-2-carboxylic acid 8-Bromo-3-methyl xanthine Maleic hydrazide o-Anisaldehyde 4-Bromobenzaldehyde 3-Fluorobenzaldehyde 2-Chlorobenzaldehyde 3-Amino-3-(3-fluorophenyl)propanoic acid 1-Propyl-4-piperidone 2,3-Dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-1H-inden-1-one hydrochloride 3-(4-Bromo-3-methyl-2-oxo-2,3-dihydro-1h-benzo[d]imidazol-1-yl)piperidine-2,6-dione 2-Fluoro-6-iodobenzoic acid 3-Pyridineacrylic acid 1-Boc-4-cyanopiperidine ethyl 2-oxo-2,3,9,10-tetrahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline-8(7H)-carboxylate Vardenafil Bis-sulphonamide(Dimer) Nitroso Irbesartan N-Nitroso Nortriptyline Sulfonic acid Impurity 2-(p-Tolyl)acetaldehyde 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-oneRelated products of tetrahydrofuran
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