Ethyl N-Boc-piperidine-4-carboxylate
Synonym(s):Ethyl 1-(tert-butoxycarbonyl)-4-piperidinecarboxylate;Ethyl 1-(tert-Butyloxycarbonyl)isonipecotate;Piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester
- CAS NO.：142851-03-4
- Empirical Formula: C13H23NO4
- Molecular Weight: 257.33
- MDL number: MFCD01763998
- EINECS: 000-000-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-24 18:13:44
What is Ethyl N-Boc-piperidine-4-carboxylate?
Chemical properties
Liquid
The Uses of Ethyl N-Boc-piperidine-4-carboxylate
Ethyl N-Boc-piperidine-4-carboxylate is used as a reagent to synthesize 3-amino-1-(5-indanyloxy)-2-propanol derivatives as sodium channel blockers to treat stroke patients. Ethyl N-Boc-piperidine-4-carboxylate is also used as a reagent to prepare inhibitors of tumour necrosis factor alpha-converting enzyme.
The Uses of Ethyl N-Boc-piperidine-4-carboxylate
Substrate used in a palladium-catalyzed α-arylation of esters with heterocyclic bromides and chlorides leading to, for example, 4-pyridylpiperidinyl esters.
Properties of Ethyl N-Boc-piperidine-4-carboxylate
| Boiling point: | 120-135 °C/0.5 mmHg |
| Density | 1.046 g/mL at 25 °C |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform, Ethyl Acetate |
| form | Liquid |
| pka | -2.23±0.40(Predicted) |
| color | Clear colorless to pale yellow |
| CAS DataBase Reference | 142851-03-4(CAS DataBase Reference) |
Safety information for Ethyl N-Boc-piperidine-4-carboxylate
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for Ethyl N-Boc-piperidine-4-carboxylate
| InChIKey | MYHJCTUTPIKNAT-UHFFFAOYSA-N |
Ethyl N-Boc-piperidine-4-carboxylate manufacturer
JSK Chemicals
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Phone:+91-9879767984
Whatsapp: +91-9879767970
product: Ethyl N-Boc-piperidine-4-carboxylate, 99%
NSR Amino Organics
1Y
Phone:+91-9866989891
Whatsapp: +91-9866989891
product: Ethyl N-Boc-Piperdine-4-Carboxylate 142851-03-4 98%
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