Ethyl difluoroacetate
- CAS NO.：454-31-9
- Empirical Formula: C4H6F2O2
- Molecular Weight: 124.09
- MDL number: MFCD00013578
- EINECS: 207-223-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:17:34
What is Ethyl difluoroacetate?
Chemical properties
clear colorless liquid
The Uses of Ethyl difluoroacetate
Ethyl difluoroacetate is used in pharmaceutical intermediates, acrylization oxidation and halogenating reaction of catalyst. Also ethyl difluoroacetate is used in preparing pyrrazolo-pyrimidine derivatives.
General Description
Ethyl difluoroacetate was degraded to difluoroacetic acid by the strains of Actinobacteria.
Properties of Ethyl difluoroacetate
| Boiling point: | 99.2 °C (lit.) |
| Density | 1.18 g/mL at 25 °C (lit.) |
| vapor pressure | 30.03-200.2hPa at 20.03-56.98℃ |
| refractive index | 1.3465-1.3485 |
| Flash point: | 25 °C |
| storage temp. | 2-8°C |
| solubility | DMSO (Sparingly), Methanol (Sparingly) |
| form | Liquid |
| color | Clear colorless |
| Specific Gravity | 1.242 |
| Water Solubility | Slightly soluble in water |
| BRN | 1748597 |
| CAS DataBase Reference | 454-31-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Acetic acid, difluoro-, ethyl ester(454-31-9) |
| EPA Substance Registry System | Acetic acid, difluoro-, ethyl ester (454-31-9) |
Safety information for Ethyl difluoroacetate
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H226:Flammable liquids H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Ethyl difluoroacetate
| InChIKey | GZKHDVAKKLTJPO-UHFFFAOYSA-N |
Ethyl difluoroacetate manufacturer
JSK Chemicals
3Y
Phone:+91-9879767984
Whatsapp: +91-9879767970
product: Ethyl difluoroacetate, 98% 99%
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