Ethyl benzimidate hydrochloride

CAS NO.：5333-86-8
Empirical Formula: C9H12ClNO
Molecular Weight: 185.65
MDL number: MFCD00043246
EINECS: 226-248-1
SAFETY DATA SHEET (SDS)
Update Date: 2025-01-27 09:38:02

What is Ethyl benzimidate hydrochloride?

Chemical properties

White to white crystalline

The Uses of Ethyl benzimidate hydrochloride

Ethyl benzimidate hydrochloride is used in the preparation of (4R)-ethyl 2-phenyl-4,5-dihydrothiazole-4-carboxylate by reacting with (R)-ethyl cysteine hydrochloride. It also reacts with D-penicillamine methyl ester hydrochloride and triethylamine to prepare methyl-5,5- dimethyl-2-phenyl-2-thiazoline-4-carboxylate. Further, it is used as an intermediate for organic synthesis.

The Uses of Ethyl benzimidate hydrochloride

Intermediate for synthesis

What are the applications of Application

Ethyl benzimidate hydrochloride is a compound that reacts with (R)-ethyl cysteine hydrochloride

General Description

Ethyl benzimidate hydrochloride reacts with (R)-ethyl cysteine hydrochloride in ethanol to yield (4R)-ethyl 2-phenyl-4,5-dihydrothiazole-4-carboxylate. It reacts with D-Penicillamine methyl ester hydrochloride and triethylamine to yield methyl-5,5- dimethyl-2-phenyl-2-thiazoline-4-carboxylate.

Properties of Ethyl benzimidate hydrochloride

Melting point:	~125 °C (dec.)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
color	White
Water Solubility	Soluble in water.
Sensitive	Hygroscopic
BRN	3697589
EPA Substance Registry System	Benzenecarboximidic acid, ethyl ester, hydrochloride (5333-86-8)

Safety information for Ethyl benzimidate hydrochloride

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.