ETHYL 5-METHYLINDOLE-2-CARBOXYLATE
Synonym(s):5-Methylindole-2-carboxylic acid ethyl ester;NSC 30928
- CAS NO.：16382-15-3
- Empirical Formula: C12H13NO2
- Molecular Weight: 203.24
- MDL number: MFCD00022703
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:20:11
What is ETHYL 5-METHYLINDOLE-2-CARBOXYLATE?
The Uses of ETHYL 5-METHYLINDOLE-2-CARBOXYLATE
Reactant for synthesis of oxazino[4,3-a]indoles via cascade addition-cyclization reactions 1 Reactant for preparation of indolecarboxamides as cannabinoid CB1 receptor antagonists 2 Reactant for preparation of indole-3-propionic acids as antiinflammatory and analgesic agents 3 Reactant for Friedel-Crafts acylation with nitrobenzoyl chloride 4 Reactant for oximation reactions 5
The Uses of ETHYL 5-METHYLINDOLE-2-CARBOXYLATE
Reactant for synthesis of oxazino[4,3-a]indoles via cascade addition-cyclization reactions, reactant for preparation of indolecarboxamides as cannabinoid CB1 receptor antagonists, reactant for preparation of indole-3-propionic acids as antiinflammatory and analgesic agents, reactant for Friedel-Crafts acylation with nitrobenzoyl chloride. Indole ring system is an important building block or intermediate in the synthesis of many pharmaceutical agents. It is formed during the Fischer indolization of ethyl pyruvate 2-[2-(methanesulfonyloxy)-4-methyl]phenylhydrazine. ? Reactant for oximation reactions
What are the applications of Application
Ethyl 5-methylindole-2-carboxylate is a compound for the synthesis of biological active chemicals
General Description
Ethyl 5-methylindole-2-carboxylate (5-Methylindole-2-carboxylic acid ethyl ester) is an indole derivative. Indole ring system is an important building block or intermediate in the synthesis of many pharmaceutical agents. It is formed during the Fischer indolization of ethyl pyruvate 2-[2-(methanesulfonyloxy)-4-methyl]phenylhydrazine.
Properties of ETHYL 5-METHYLINDOLE-2-CARBOXYLATE
| Melting point: | 162-164°C |
| Boiling point: | 236°C 4mm |
| Density | 1.177±0.06 g/cm3(Predicted) |
| Flash point: | 236°C/4mm |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 15.19±0.30(Predicted) |
| color | Light yellow to beige |
| Water Solubility | Soluble in methanol, and dichloromethane. Insoluble in water. |
| BRN | 159437 |
| CAS DataBase Reference | 16382-15-3(CAS DataBase Reference) |
Safety information for ETHYL 5-METHYLINDOLE-2-CARBOXYLATE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305:IF IN EYES: P351:Rinse cautiously with water for several minutes. |
Computed Descriptors for ETHYL 5-METHYLINDOLE-2-CARBOXYLATE
New Products
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