Ertugliflozin L-pyroglutamic acid
- CAS NO.：1210344-83-4
- Empirical Formula: C27H32ClNO10
- Molecular Weight: 566
- MDL number: MFCD27956909
- Update Date: 2025-12-04 16:42:01
What is Ertugliflozin L-pyroglutamic acid?
Description
Ertugliflozin L-pyroglutamic acid is a potent, selective, orally active sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor with an IC50 value of 0.877 nM for h-SGLT2.It is the main active ingredient in the tablet ertugliflozin. It is the main active ingredient of ertugliflozin tablets. It is used as an adjunctive therapy for type 2 diabetes.
Chemical properties
Ertugliflozin L-pyroglutamic acid is a white to off-white powder, soluble in ethanol and acetone, slightly soluble in ethyl acetate and acetonitrile, and very slightly soluble in water.
The Uses of Ertugliflozin L-pyroglutamic acid
Ertugliflozin L-pyroglutamic Acid is a reagent in the synthesis of Ertugliflozin (1210344-57-2) a sodium/glucose cotransporter 2 (SGLT2) inhibitor used to treat type 2 diabetes.
brand name
STEGLATRO
Properties of Ertugliflozin L-pyroglutamic acid
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | DMSO: ≥ 125 mg/mL (220.85 mM) |
| form | Solid |
| color | White to off-white |
Safety information for Ertugliflozin L-pyroglutamic acid
Computed Descriptors for Ertugliflozin L-pyroglutamic acid
| InChIKey | YHIUPZFKHZTLSH-NCRAORDPNA-N |
| SMILES | C([C@@H]1CCC(=O)N1)(=O)O.O[C@@H]1[C@H]([C@H](O)[C@]2(CO)CO[C@@]1(C1C=CC(Cl)=C(CC3C=CC(OCC)=CC=3)C=1)O2)O |&1:1,10,11,12,14,19,r| |
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