Eritoran
- CAS NO.：185955-34-4
- Empirical Formula: C66H126N2O19P2
- Molecular Weight: 1313.66
- MDL number: MFCD09260033
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:35
What is Eritoran?
Description
Eritoran, a complex molecule with two hexose rings and two phosphate groups, blocks the inflammation pathway mediated by Toll-like receptor (TLR) 4. This mechanism is present in sepsis, but late-stage clinical trials on eritoran failed to show activity against that condition.
Recently, S. N. Vogel and colleagues at the University of Maryland, Baltimore, showed that?eritoran combats flu in rodents. Instead of attacking the flu virus, it treats TLR 4–related inflammation and prevents lung damage.
The Uses of Eritoran
Treatment of sepsis and other diseases due to reaction to bacterial endotoxin (endotoxin antagonist).
Definition
ChEBI: Eritoran is a lipid A derivative used for the treatment of severe sepsis. It is a conjugate acid of an eritoran(4-).
Properties of Eritoran
| Density | 1.14 |
| pka | 1.73±0.10(Predicted) |
| CAS DataBase Reference | 185955-34-4(CAS DataBase Reference) |
Safety information for Eritoran
Computed Descriptors for Eritoran
New Products
N-Carbethoxy-4-piperidone 1-Aminocyclopentane carbonitrile Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine N-Vinylformamide 4 pentyn 1 ol Phenethyl cinnamate Dipropyl disulfide Ethyl 3-phenylpropanoate β-Bromostyrene Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 5-Bromo-1-Pentyne 1-(2-Methyl-5-nitrophenyl)guanidine Nitrate Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide 2-Pentyn-1-oL 4-NitrobenzotrifluorideRelated products of tetrahydrofuran
You may like
-
144-83-2 Sulfapyridine 98+View Details
144-83-2 -
29976-53-2 98+View Details
29976-53-2 -
2-Amino-5-bromo-4-(trifluoromethyl)pyridine 98+View Details
944401-56-3 -
(RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 39773-47-2 98+View Details
39773-47-2 -
6638-79-5 N,O-Dimethylhydroxylamine hydrochloride 98+View Details
6638-79-5 -
674783-97-2 98+View Details
674783-97-2 -
1-Aminocyclopentane carbonitrile 98+View Details
49830-37-7 -
Tetrabutylammonium perchlorate 1923-70-2 98+View Details
1923-70-2
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.