Eritoran
- CAS NO.：185955-34-4
- Empirical Formula: C66H126N2O19P2
- Molecular Weight: 1313.66
- MDL number: MFCD09260033
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:35
What is Eritoran?
Description
Eritoran, a complex molecule with two hexose rings and two phosphate groups, blocks the inflammation pathway mediated by Toll-like receptor (TLR) 4. This mechanism is present in sepsis, but late-stage clinical trials on eritoran failed to show activity against that condition.
Recently, S. N. Vogel and colleagues at the University of Maryland, Baltimore, showed that?eritoran combats flu in rodents. Instead of attacking the flu virus, it treats TLR 4–related inflammation and prevents lung damage.
The Uses of Eritoran
Treatment of sepsis and other diseases due to reaction to bacterial endotoxin (endotoxin antagonist).
Definition
ChEBI: Eritoran is a lipid A derivative used for the treatment of severe sepsis. It is a conjugate acid of an eritoran(4-).
Properties of Eritoran
| Density | 1.14 |
| pka | 1.73±0.10(Predicted) |
| CAS DataBase Reference | 185955-34-4(CAS DataBase Reference) |
Safety information for Eritoran
Computed Descriptors for Eritoran
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