HEPPS
Synonym(s):N-(2-Hydroxyethyl)piperazine-N′-(3-propanesulfonic acid);4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic acid;4-(2-Hydroxyethyl)piperazine-1-propanesulfonic acid;HEPPS
- CAS NO.:16052-06-5
- Empirical Formula: C9H20N2O4S
- Molecular Weight: 252.33
- MDL number: MFCD00006160
- EINECS: 240-198-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is HEPPS?
Chemical properties
white crystalline powder
The Uses of HEPPS
EPPS is a commonly used Good?s buffer. It is often used as separator in ultrathin isoelectric focusing gels and enhances the resolution of phosphoglucomutase. It is used as a buffering agent in biology and biochemistry.
What are the applications of Application
HEPPS is also called EPPS, a biological buffer with a useful pH range of 7.3-8.7 & pKa=8.0 (25°C)
Definition
ChEBI: HEPPS is a N-(sulfoalkyl)piperazine and a N-(2-hydroxyethyl)piperazine.
Flammability and Explosibility
Not classified
Properties of HEPPS
| Melting point: | 237-239 °C(lit.) |
| Density | 1.2684 (rough estimate) |
| refractive index | 1.6800 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | H2O: 1 M at 20 °C, clear, colorless |
| form | Powder/Solid |
| color | White |
| PH | 5.0-6.5 (25℃, 0.1M in H2O) |
| pka | 8.0(at 25℃) |
| PH Range | 7.3 - 8.7 |
| Water Solubility | Soluble in water. 25.2 g/L (20°C) |
| λmax | λ: 260 nm Amax: 0.055 λ: 280 nm Amax: 0.045 |
| BRN | 3957385 |
| CAS DataBase Reference | 16052-06-5(CAS DataBase Reference) |
| EPA Substance Registry System | 1-Piperazinepropanesulfonic acid, 4-(2-hydroxyethyl)- (16052-06-5) |
Safety information for HEPPS
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for HEPPS
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![2-HYDROXY-3-(4-[(4-HYDROXYPHENOXY)ACETYL]PIPERAZIN-1-YL)PROPANE-1-SULFONIC ACID](https://img.chemicalbook.in/StructureFile/ChemBookStructure7/GIF/CB8286646.gif)
![[4-(2-HYDROXY-3-SULFO-PROPYL)-PIPERAZIN-1-YL]-OXO-ACETIC ACID](https://img.chemicalbook.in/StructureFile/ChemBookStructure7/GIF/CB1399291.gif)
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