ELOCALCITOL
- CAS NO.：199798-84-0
- Empirical Formula: C29H43FO2
- Molecular Weight: 442.65
- MDL number: MFCD09954119
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-16 07:06:08
What is ELOCALCITOL?
Description
BXL-628 is an analog of vitamin D3 that has diverse biological activities. It increases death of androgen-stimulated human benign prostatic hyperplasia (BPH) cells via induction of apoptosis in a dose-dependent manner. In vivo, BXL-628 completely inhibits androgen-stimulated prostate overgrowth in a rat model of BPH. It reduces expression of IL-13 and IgE/mast cell-derived protease 1 (MMCP1) and decreases edema and leukocyte infiltration in the bladder wall in a mouse model of allergen-induced interstitial cystitis. BXL-628 also reduces the number of adherent endometrial stromal cells and decreases the total weight of endometrial lesions in a mouse model of endometriosis. Formulations containing BXL-628 are under clinical investigation for the treatment of BPH.
Properties of ELOCALCITOL
| Boiling point: | 568.3±50.0 °C(Predicted) |
| Density | 1.05±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Ethanol:20.0(Max Conc. mg/mL);45.18(Max Conc. mM) |
| form | A crystalline solid |
| pka | 14.04±0.40(Predicted) |
| color | White to off-white |
Safety information for ELOCALCITOL
Computed Descriptors for ELOCALCITOL
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