EC 3.1.4.4 TYPE IV

Synonym(s):Lecithinase D;Phosphatidylcholine phosphatidohydrolase;Phospholipase D from white cabbage;Phospholipase D, Streptomyces chromofuscus;PLD

CAS NO.：9001-87-0
Empirical Formula: NULL
Molecular Weight: 0
MDL number: MFCD00131897
EINECS: 232-639-8
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-27 23:21:39

What is EC 3.1.4.4 TYPE IV?

The Uses of EC 3.1.4.4 TYPE IV

Phospholipase D from Streptomyces chromofuscus has been used to cleave choline-containing phospholipids (PCs).

The Uses of EC 3.1.4.4 TYPE IV

Phospholipase D (PLD) is used to hydrolyze the phosphate bonds of phospholipids and sphingomyelin to give the corresponding phosphatidic acid. It has also been used to study metabolic labeling and direct imaging of choline phospholipids in vivo by measuring propargyl-Cho incorporation. Furthermore, PLD is used in purification and kinetic studies.

General Description

Phospholipase D (phosphatidylcholine cholinehydrolase, EC 3.1.4.4) is a ubiquitous enzyme with a molecular weight of ~ 50,000Da. It is expressed in a variety of plant tissues, few microorganisms and some mammalian tissues.

Biochem/physiol Actions

Phospholipase D is glycerophospholipid-specific. It is markedly less active on sphingomyelins and lysophospholipids. Phospholipase D hydrolyzes the phosphate bonds of phospholipids and sphingomyelin to give the corresponding phosphatidic acid.

Properties of EC 3.1.4.4 TYPE IV

storage temp.	-70°C
form	lyophilized powder
color	Light yellow to yellow

Safety information for EC 3.1.4.4 TYPE IV

Signal word	Danger
Pictogram(s)	Health Hazard GHS08
GHS Hazard Statements	H334:Sensitisation, respiratory
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P284:Wear respiratory protection. P501:Dispose of contents/container to..…