EC 3.1.4.3
Synonym(s):PLC;1-Phosphatidyl-D -myo-inositol inositol phosphohydrolase, cyclic-phosphate forming;Lecithinase C;Lipophosphodiesterase I;PC-PLC
- CAS NO.：9001-86-9
- Molecular Weight: 0
- MDL number: MFCD00131895
- EINECS: 232-638-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:24:06
What is EC 3.1.4.3?
The Uses of EC 3.1.4.3
Phospholipase C from Clostridium perfringens has been used as a positive control in sandwich enzyme linked immunosorbent assay (ELISA) and ELISA.
The Uses of EC 3.1.4.3
Phospholipase C (PLC) has been used to study adrenoceptor-mediated transmembrane signaling. It is also used to degrade inositol-containing phospholipids. Furthermore, it has been used to study 9E3 gene activation.
The Uses of EC 3.1.4.3
The enzyme from Sigma has been used in the digestion of phosphatidylserine fraction of Schistosoma mansoni adult worms.
General Description
This product has been enhanced for energy efficiency and waste prevention when used in biodiesel research.
Biochem/physiol Actions
PLC hydrolyzes the phosphate bond on phosphatidylcholine and other glycerophospholipids yielding diacylglycerol. This enzyme also hydrolyzes the phosphate bonds of sphingomyelin, cardiolipin, choline plasmalogen and ceramide phospholipids. Phospholipase C is induced by thrombin and platelet-activating factor, forming 1,2-diacylglycerol and phosphatidic acid.
Properties of EC 3.1.4.3
| storage temp. | -20°C |
| solubility | H2O: soluble1.0mg/mL, faintly hazy to hazy |
| form | powder |
| color | slightly beige |
| EPA Substance Registry System | Phospholipase C (9001-86-9) |
Safety information for EC 3.1.4.3
| Signal word | Danger |
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H334:Sensitisation, respiratory |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P284:Wear respiratory protection. P501:Dispose of contents/container to..… |
Computed Descriptors for EC 3.1.4.3
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