EBELACTONE A
Synonym(s):3,11-Dihydroxy-2,4,6,8,10,12-hexamethyl-9-oxo-6-tetradecenoic acid 1,3-lactone
- CAS NO.：76808-16-7
- Empirical Formula: C20H34O4
- Molecular Weight: 338.48
- MDL number: MFCD00036710
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-27 16:16:43
What is EBELACTONE A?
Description
Ebelactone A is a β-lactone enzyme inhibitor that was first isolated from a cultured strain of soil actinomycetes. It can inhibit esterases, lipases, and N-formylmethionine aminopeptidases (IC50s = 0.056, 0.003, and 0.08 μg/ml, respectively) found on cell surfaces, which has been shown to stimulate host defense in immune cells. Ebelactone A is also reported to inhibit cutinases produced by fungal pathogens, thus demonstrating a plant-protective function.
What are the applications of Application
Ebelactone A is an inhibitor of esterase, formyl methionine aminopeptidase, and acylpeptide hydrolase
Properties of EBELACTONE A
| storage temp. | 2-8°C |
| solubility | DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 25 mg/ml; Ethanol: 20 mg/ml |
| form | White crystalline powder. |
Safety information for EBELACTONE A
Computed Descriptors for EBELACTONE A
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