E-PHENYLETHENYLBORONIC ACID

Synonym(s):(E)-2-phenyl-Etheneboronic acid;(E)-Phenylethenylboronic acid;(E)-Styreneboronic acid;(E)-Styrylboronic acid;trans-(2-Phenylethenyl)boronic acid

CAS NO.：6783-05-7
Empirical Formula: C8H9BO2
Molecular Weight: 147.97
MDL number: MFCD00963621
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 02:29:27

What is E-PHENYLETHENYLBORONIC ACID?

Chemical properties

Brown granular powder

The Uses of E-PHENYLETHENYLBORONIC ACID

E-Phenylethenylboronic acid is a reagent used for• ;Palladium (Pd)-catalyzed Suzuki-Miyaura coupling reactions
1 Rhodium (Rh)-catalyzed intramolecular amination of aryl azides
2 Diastereoselective synthesis via Pd-catalyzed Heck-Suzuki cascade reaction
3 Copper (Cu)-mediated cyanation
4 Rhodium (Rh)-catalyzed asymmetric addition
5 Diastereoselective synthesis via iridium (Ir)-catalyzed addition
6 Palladium (Pd)-catalyzed cascade cyclization
7 Reagent used in Preparation of • ;Optically active unsaturated amino acids by diastereoselective Petasis borono-Mannich reactio

The Uses of E-PHENYLETHENYLBORONIC ACID

trans-beta-Styrylboronic acid as reagent is used for palladium (Pd)-catalyzed Suzuki-Miyaura coupling reactions, diastereoselective synthesis via Pd-catalyzed Heck-Suzuki cascade reaction and rhodium (Rh)-catalyzed intramolecular amination of aryl azides. It is also used as reagent in preparation of optically active unsaturated amino acids by diastereoselective Petasis borono-Mannich reaction and amino alcohol dienes via Petasis 3-component reaction using Ru-catalyzed ring-closing metathesis and isomerization.

The Uses of E-PHENYLETHENYLBORONIC ACID

Reagent used for

Palladium (Pd)-catalyzed Suzuki-Miyaura coupling reactions
Rhodium (Rh)-catalyzed intramolecular amination of aryl azides
Diastereoselective synthesis via Pd-catalyzed Heck-Suzuki cascade reaction
Copper (Cu)-mediated cyanation
Rhodium (Rh)-catalyzed asymmetric addition
Diastereoselective synthesis via iridium (Ir)-catalyzed addition
Palladium (Pd)-catalyzed cascade cyclization

Reagent used in Preparation of

Optically active unsaturated amino acids by diastereoselective Petasis borono-Mannich reaction
Amino alcohol dienes via Petasis 3-component reaction using Ru-catalyzed ring-closing metathesis and isomerization

What are the applications of Application

trans-2-Phenylvinylboronic acid is used in palladium catalyzed and Suzuki coupling reactions

Properties of E-PHENYLETHENYLBORONIC ACID

Melting point:	146-156 °C(lit.)
Boiling point:	315.9±35.0 °C(Predicted)
Density	1.130±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Store in freezer, under -20°C
form	Powder and/or Chunks
pka	9.38±0.43(Predicted)
color	Light yellow to beige
CAS DataBase Reference	6783-05-7(CAS DataBase Reference)

Safety information for E-PHENYLETHENYLBORONIC ACID

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.