5,6-Benzoflavone
Synonym(s):5,6-Benzoflavone;beta-Naphthoflavone;BNF
- CAS NO.：6051-87-2
- Empirical Formula: C19H12O2
- Molecular Weight: 272.3
- MDL number: MFCD00004986
- EINECS: 227-958-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-06-03 11:24:09
What is 5,6-Benzoflavone?
Chemical properties
SLIGHTLY BEIGE CRYSTALLINE POWDER
The Uses of 5,6-Benzoflavone
beta-Naphthoflavone is a Cytochrome P450 enzyme system inducer. It can also be used in biological study of novel dual-color luciferase reporter assay for simultaneous detection of estrogen and aryl hydrocarbon receptor activation.
What are the applications of Application
β-Naphthoflavone is a Cytochrome P450 enzyme system inducer
Definition
ChEBI: An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone.
General Description
β-Naphthoflavone is a polyaromatic hydrocarbon.
Biochem/physiol Actions
β-Naphthoflavone (BNF) is an exogenous ligand for aryl hydrocarbon receptor (AhR) in humans. It is an inducer of phase I detoxification enzymes (CYPs) and phase II enzymes (UDP-GTs) and NAD(P)H-dependent quinone oxyreductase-1(NQO1). It also induces cytochrome P450 (Cyp1a). BNF represses the expression of Duchenne muscular dystrophy gene, dystrophin (Dp)71 by altering the binding of the transcription factors.
Properties of 5,6-Benzoflavone
| Melting point: | 164-166 °C (lit.) |
| Boiling point: | 275-280 °C (1 mmHg) |
| Density | 1.1382 (rough estimate) |
| refractive index | 1.5510 (estimate) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly, Heated) |
| form | Crystalline Powder |
| color | yellow to tan |
| BRN | 18991 |
| CAS DataBase Reference | 6051-87-2(CAS DataBase Reference) |
Safety information for 5,6-Benzoflavone
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 5,6-Benzoflavone
New Products
2-Amino-5-bromo- benzoic acid 2-Benzyl-1,1,3,3-tetramethylisoindoline Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One Cis-Tosylate 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) 1-aminocyclobutanecarbonitrile hydrochloride AMINO-O-TOLYL-ACETIC ACID 1-Aminocyclobutanecarboxylic Acid Hydrochloride AMINO(2-BROMOPHENYL)ACETIC ACID 6-BROMOTETRAZOLO[1,5-A]PYRIDINE 3-Oxocyclobutanecarboxylic acid METHANOL-D1(OD) TERTIARY BUTANOL-D9 N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D TOLUENE-D3 3-tert-Butyl-5-bromobenzaldehyde Methyl 6-(hydroxymethyl)nicotinate 4-Bromo-3-iodoaniline 4-(piperazin-1-yl)benzene-1,2-diamine 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
You may like
-
β-Naphthoflavone CAS 6051-87-2View Details
6051-87-2 -
Beta-naphthoflavone 95% CAS 6051-87-2View Details
6051-87-2 -
β-Naphthoflavone CAS 6051-87-2View Details
6051-87-2 -
254762-66-8 AMINO(2-BROMOPHENYL)ACETIC ACID 98+View Details
254762-66-8 -
6-BROMOTETRAZOLO[1,5-A]PYRIDINE 98+View Details
5799-75-7 -
254762-66-8 AMINO(2-BROMOPHENYL)ACETIC ACID 98+View Details
254762-66-8 -
23716-23-1 98+View Details
23716-23-1 -
6-BROMOTETRAZOLO[1,5-A]PYRIDINE 98+View Details
5799-75-7