Dolutegravir 2-Desfluoro Impurity
- CAS NO.：1863916-88-4
- Empirical Formula: C20H20FN3O5
- Molecular Weight: 401.39
- Update Date: 2023-07-12 17:02:14
What is Dolutegravir 2-Desfluoro Impurity?
The Uses of Dolutegravir 2-Desfluoro Impurity
Defluoro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
Properties of Dolutegravir 2-Desfluoro Impurity
| Boiling point: | 675.7±55.0 °C(Predicted) |
| Density | 1.49±0.1 g/cm3(Predicted) |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| pka | 4.50±1.00(Predicted) |
| form | Solid |
| color | Off-White to Light Brown |
Safety information for Dolutegravir 2-Desfluoro Impurity
Computed Descriptors for Dolutegravir 2-Desfluoro Impurity
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