DNQX
Synonym(s):6,7-Dinitroquinoxaline-2,3(1H,4H)-dione;AMPA Glutamate Receptor Antagonist, DNQX, Kainate Glutamate Receptor Antagonist, DNQX;DNQX Disodium Salt - CAS 2379-57-9 - Calbiochem
- CAS NO.:2379-57-9
- Empirical Formula: C8H4N4O6
- Molecular Weight: 252.14
- MDL number: MFCD00069257
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 10:31:43
What is DNQX?
Chemical properties
Off-White Powder with a Yellow Tinge
The Uses of DNQX
DNQX has been used to block N-Methyl-D-aspartic acid (NMDA) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors in various experiments.
The Uses of DNQX
Potent competitive non-NMDA glutamate receptor antagonist
What are the applications of Application
6,7-Dinitroquinoxaline-2,3-dione (DNQX) is a non-NMDA receptor complex antagonist
Definition
ChEBI: 6,7-dinitro-1,4-dihydroquinoxaline-2,3-dione is a quinoxaline derivative.
Biological Activity
Water-soluble form of 6,7-Dinitroquinoxaline-2,3-dione . Selective non-NMDA receptor antagonist.
Biochem/physiol Actions
DNQX is a quinoxaline derivative.
Storage
Room temperature
Properties of DNQX
| Melting point: | >300°C |
| Boiling point: | 395.32°C (rough estimate) |
| Density | 1.6919 (rough estimate) |
| refractive index | 1.6700 (estimate) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Soluble in DMSO |
| pka | 7.68±0.20(Predicted) |
| form | Pale yellow solid. |
| color | Off-White to Light Yellow |
| Stability: | Store in freezer at -20°C |
| CAS DataBase Reference | 2379-57-9(CAS DataBase Reference) |
Safety information for DNQX
Computed Descriptors for DNQX
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