DMEOB
Synonym(s):3-Methoxybenzaldehyde [(3-methoxyphenyl)methylene]hydrazone
- CAS NO.：40252-74-2
- Empirical Formula: C16H16N2O2
- Molecular Weight: 268.31
- MDL number: MFCD01001892
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 00:03:05
What is DMEOB?
The Uses of DMEOB
DMEOB is a negative allosteric modulator at mGluR-5 (1). These mGlu receptors maintain a modulatory role and act as drug targets for various neurological disorders including depression, schizophrenia and Parkinson’s.
What are the applications of Application
DMEOB is a negative allosteric modulator at mGluR-5
Biological Activity
Negative allosteric modulator of the metabotropic glutamate receptor mGlu 5 ; displays reversible non-competitive inhibition of mGlu 5 -mediated responses (IC 50 = 3 μ M).
Biochem/physiol Actions
Negative allosteric modulator at the metabotropic glutamate receptor mGluR5.
Properties of DMEOB
| Melting point: | 77-78 °C(Solv: ethanol (64-17-5)) |
| Boiling point: | 405.1±45.0 °C(Predicted) |
| Density | 1.05±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | H2O: insoluble |
| form | solid |
| pka | 6.46±0.50(Predicted) |
| color | yellow |
Safety information for DMEOB
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Environment GHS09 |
| GHS Hazard Statements |
H318:Serious eye damage/eye irritation H400:Hazardous to the aquatic environment, acute hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for DMEOB
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