DMEOB
Synonym(s):3-Methoxybenzaldehyde [(3-methoxyphenyl)methylene]hydrazone
- CAS NO.：40252-74-2
- Empirical Formula: C16H16N2O2
- Molecular Weight: 268.31
- MDL number: MFCD01001892
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-22 18:57:36
What is DMEOB?
The Uses of DMEOB
DMEOB is a negative allosteric modulator at mGluR-5 (1). These mGlu receptors maintain a modulatory role and act as drug targets for various neurological disorders including depression, schizophrenia and Parkinson’s.
What are the applications of Application
DMEOB is a negative allosteric modulator at mGluR-5
Biological Activity
Negative allosteric modulator of the metabotropic glutamate receptor mGlu 5 ; displays reversible non-competitive inhibition of mGlu 5 -mediated responses (IC 50 = 3 μ M).
Biochem/physiol Actions
Negative allosteric modulator at the metabotropic glutamate receptor mGluR5.
Properties of DMEOB
| Melting point: | 77-78 °C(Solv: ethanol (64-17-5)) |
| Boiling point: | 405.1±45.0 °C(Predicted) |
| Density | 1.05±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | H2O: insoluble |
| form | solid |
| pka | 6.46±0.50(Predicted) |
| color | yellow |
Safety information for DMEOB
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Environment GHS09 |
| GHS Hazard Statements |
H318:Serious eye damage/eye irritation H400:Hazardous to the aquatic environment, acute hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for DMEOB
New Products
3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Pentadecanoic acid Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 5-Bromo-2-Fluoropyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4-Bromo-3-(ethoxymethyl)benzoic acid 2,4-Dichloro-5-methoxyaniline 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine N2-Isobutyryl-2'-O-methylguanosine 2-chloro-5-methylpyridin-4-amine 4-Bromobenzaldehyde 2-Chloro-6-nitro benzothiazole 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amineRelated products of tetrahydrofuran
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