DL-Penicillamine
- CAS NO.：52-66-4
- Empirical Formula: C5H11NO2S
- Molecular Weight: 149.21
- MDL number: MFCD00004856
- EINECS: 200-147-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:51:19
What is DL-Penicillamine?
Chemical properties
white to almost white crystalline powder
The Uses of DL-Penicillamine
DL-Penicillamine is a penicillin metabolite used in the treatment of Wilson’s disease, Cystinuria, Scleroderma and arsenic poisoning.
The Uses of DL-Penicillamine
antirheumatic, chelating agent (copper), Wilson's desease treatment
Definition
ChEBI: An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Safety Profile
Poison by ingestion and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx.
Properties of DL-Penicillamine
| Melting point: | 204-208 °C(lit.) |
| Boiling point: | 251.8±35.0℃ (760 Torr) |
| Density | 1.204±0.06 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.5216 (estimate) |
| Flash point: | 106.1±25.9℃ |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | Methanol (Slightly), Water (Soluble) |
| pka | pK: 1.8 (carboxyl); 7.9 (a-amino); 10.5 (b-thiol) |
| form | solid |
| Water Solubility | Soluble in ethanol, hot water and sodium hydroxide. |
| Merck | 14,7088 |
| BRN | 2039817 |
| CAS DataBase Reference | 52-66-4(CAS DataBase Reference) |
Safety information for DL-Penicillamine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for DL-Penicillamine
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