DL-KYNURENINE
Synonym(s):2-Amino-3-(2-aminobenzoyl)propionic acid;2-Amino-4-(2-aminophenyl)-4-oxobutyric acid
- CAS NO.：343-65-7
- Empirical Formula: C10H12N2O3
- Molecular Weight: 208.22
- MDL number: MFCD00025194
- EINECS: 206-445-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 23:13:44
What is DL-KYNURENINE?
The Uses of DL-KYNURENINE
A tryptophan metabolite, is a precursor of kynurenic acid, which is an antagonist of N-methyl-aspartate receptor. An amino acid produced in the body from tryptophan
The Uses of DL-KYNURENINE
vasodilator, immunomodulator
The Uses of DL-KYNURENINE
A tryptophan metabolite, is a precursor of kynurenic acid, which is an antagonist of N-methyl-aspartate receptor. An amino acid produced in the body from tryptophan.
Definition
ChEBI: A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
Purification Methods
Crystallise it from H2O or aqueous AcOH. The picrate has m 188.5-189o(dec) after crystallisation from H2O. (±)-Kynurenine has m 218o. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p2726 1961, Beilstein 14 III 1657, 14 IV 2562.]
Properties of DL-KYNURENINE
| Melting point: | ~235 °C (dec.) |
| Boiling point: | 347.41°C (rough estimate) |
| Density | 1.343±0.06 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.4830 (estimate) |
| storage temp. | 2-8°C |
| solubility | Aqueous Acid (Slightly), Water (Slightly, Heated, Sonicated) |
| form | Solid |
| pka | 2.21±0.23(Predicted) |
| color | Pale Yellow to Light Yellow |
| Merck | 13,5343 |
| BRN | 2697333 |
| CAS DataBase Reference | 343-65-7(CAS DataBase Reference) |
Safety information for DL-KYNURENINE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for DL-KYNURENINE
New Products
Cyclopropane-1,1-dicarboxylic acid Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity tert-Butyl (2S)-[1-amino-3-(4-iodophenyl)-1-oxopropan-2-yl]carbamate 4-amino-2-fluoro-N- methylbenzamide 5-Chloro-3- Methyl -1,3-2-benzoxazol-2(3H)-one N-(2-chloropyrimidin-4-yl)-N,2,3- trimethyl-2H- indazol 6-amine N-Boc-1,4-butanediamine 4-Bromo-2-fluoro-N-methylbenzamide valeronitrile 3-chlorobenzyl cyanide 3,4 Dimethoxy Benzylcyanide 3,4 Diethoxy Benzylcyanide 2-Chloro Benzylcyanide 3-Hydroxypropionitrile 5-azidovalericacid 6,6'-bis(difluoromethoxy)-2,2'-bis((3,4-dimethoxypyridin-2-yl)methylsulfinyl)-1H,1'H-5,5'-bibenzo[d]imidazole (1-((2'-(2-((1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methyl)-2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol (1-((2'-(1-((1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methyl)-1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol (4-Methoxyphenyl) hydrazine HydrochlorideRelated products of tetrahydrofuran
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