DL-2-Aminoadipic acid
Synonym(s):DL -α-Aminoadipic acid
- CAS NO.：542-32-5
- Empirical Formula: C6H11NO4
- Molecular Weight: 161.16
- MDL number: MFCD00063119
- EINECS: 208-809-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:54:59
What is DL-2-Aminoadipic acid?
Chemical properties
Crystalline
The Uses of DL-2-Aminoadipic acid
DL-2-Aminoadipic acid is a labeled amino acid which is used in chemical research and as pharmaceutical intermediate.
The Uses of DL-2-Aminoadipic acid
An amino acid isolated from Cholera vibrio
What are the applications of Application
DL-2-Aminoadipic acid is a glutamine synthetase inhibitor
Definition
ChEBI: An alpha-amino acid that is adipic acid bearing a single amino substituent at position 2. An intermediate in the formation of lysine.
Biochem/physiol Actions
DL-2-Aminoadipic acid (AAA) is a six-carbon homolog of glutamate and a gliotoxic compound. It is generally used to considerably reduce the number of astroglia in cerebellar cultures that acts as a model to study the mechanisms of a-aminoadipic acid induced glial toxicity.
Purification Methods
Crystallise the acid from H2O. Alternatively purify it by precipitating the Cu salt and decomposing
Properties of DL-2-Aminoadipic acid
| Melting point: | 196-198 °C(lit.) |
| Boiling point: | 287.44°C (rough estimate) |
| Density | 1.333 |
| refractive index | 1.4230 (estimate) |
| storage temp. | 2-8°C |
| solubility | Aqueous Acid (Slightly) |
| form | Powder or Crystalline Powder |
| pka | 2.14, 4.21, 9.77(at 25℃) |
| color | White to off-white |
| Water Solubility | Soluble in water (2.2 mg/ml at 20°C), 1 M HCl (50 mg/ml), ethanol (slightly), ether (slightly), and 80% formic acid (25 mg/ml). |
| Merck | 14,416 |
| BRN | 1773077 |
| CAS DataBase Reference | 542-32-5(CAS DataBase Reference) |
Safety information for DL-2-Aminoadipic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for DL-2-Aminoadipic acid
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