Dizocilpine
- CAS NO.：77086-21-6
- Empirical Formula: C16H15N
- Molecular Weight: 221.3
- MDL number: MFCD06412575
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-11 15:21:01
What is Dizocilpine?
The Uses of Dizocilpine
Neuroprotective.
Definition
ChEBI: Dizocilpine is an organic heterotetracyclic compound that is 1-methyl-8-azabicyclo[3.2.1]octane ortho-fused to two benzene rings at positions 2-3 and 6-7 (the 5S,10R-stereoisomer). It is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor and affects cognitive function, learning, and memory. It has a role as a NMDA receptor antagonist, an anaesthetic, an anticonvulsant, a nicotinic antagonist and a neuroprotective agent. It is a secondary amino compound and a tetracyclic antidepressant. It is a conjugate base of a dizocilpine(1+).
Properties of Dizocilpine
| Melting point: | 68.5-69° |
| Boiling point: | 320.3±11.0 °C(Predicted) |
| alpha | 20589 +161.4° (c = 0.038 g/2 ml ethanol) |
| Density | 1.144±0.06 g/cm3(Predicted) |
| solubility | Soluble in DMSO > 10 mM |
| form | Powder |
| pka | 7.96±0.40(Predicted) |
| EPA Substance Registry System | 5H-Dibenzo[a,d]cyclohepten-5,10-imine, 10,11-dihydro-5-methyl-, (5S,10R)- (77086-21-6) |
Safety information for Dizocilpine
Computed Descriptors for Dizocilpine
New Products
Cis-Tosylate Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) N-BOC-piperidine-4-carboxylic acid 1-Benzhydrylazetane-3-carbonitrile AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2-(2-Chlorophenyl)glycine (±)-amino(2-fluorophenyl)acetic acid 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione BENZOIC ACID-D5 TRIFLOURO ACETICACID-D METHANE SULFONIC ACID-D4 PHOSPORIC ACID-D3 85 W% IN D2O TOLUENE-D3 BENZENE-D6 1-Acetyl-4-(4-hydroxyphenyl)piperazine 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
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